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Transthyretin proteins regulate angiogenesis by conferring different molecular ...

Nunes, R.J.; De Oliveira, P.; Lages, A.; Becker, J.D.; Marcelino, P.; Barroso, E.; Perdigoto, R.; Kelly, J.W.; Quintas, A.; Santos, S.C.R.

* This work was supported by Fundação para a Ciencia e Tecnologia Grant PIC/IC/83062/2007. The data reported in this paper have been deposited in the Gene Expression Omnibus (GEO) database,www.ncbi.nlm.nih.gov/geo (accession no. GSE44856). Supported by Fundação para a Ciencia e Tecnologia (FCT) Fellowship SFRH/BPD/43482/2008. 2 To whom correspondence should be addressed: Angiogenesis Unit, Instituto de Medicina...


The end-organ impairment in liver cirrhosis: Appointments for critical care

Figueiredo, A.; Romero-Bermejo, F.; Perdigoto, R.; Marcelino, P.

Liver cirrhosis (LC) can lead to a clinical state of liver failure, which can exacerbate through the course of the disease. New therapies aimed to control the diverse etiologies are now more effective, although the disease may result in advanced stages of liver failure, where liver transplantation (LT) remains the most effective treatment. The extended lifespan of these patients and the extended possibilities o...


Transoesophageal echocardiography for monitoring liver surgery: Data from a pil...

Pissarra, F.; Oliveira, A.; Marcelino, P.

A pilot study aimed to introduce intraoperative monitoring of liver surgery using transoesophageal echocardiography (TEE) is described. A set of TEE measurements was established as a protocol, consisting of left atrial (LA) dimension at the aortic valve plane; mitral velocity flow integral, calculation of stroke volume and cardiac output (CO); mitral annular plane systolic excursion; finally, right atrial area....


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