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Phytochemicals as Potential Epidrugs in Type 2 Diabetes Mellitus

Ramírez-Alarcón, K; Victoriano, M; Mardones, L; Villagran, M; Al-Harrasi, A; Al-Rawahi, A; Martins, N; Sharifi-Rad, J; Martorell, M

Type 2 diabetes Mellitus (T2DM) prevalence has significantly increased worldwide in recent years due to population age, obesity, and modern sedentary lifestyles. The projections estimate that 439 million people will be diabetic in 2030. T2DM is characterized by an impaired ß-pancreatic cell function and insulin secretion, hyperglycemia and insulin resistance, and recently the epigenetic regulation of ß-pancreat...


Chitosan nanoparticles as a promising tool in nanomedicine with particular emph...

Sharifi-Rad, J; Quispe, C; Butnariu, M; Rotariu, LS; Sytar, O; Sestito, S; Rapposelli, S; Akram, M; Iqbal, M; Krishna, A; Kumar, NVA; Braga, SS

The study describes the current state of knowledge on nanotechnology and its utilization in medicine. The focus in this manuscript was on the properties, usage safety, and potentially valuable applications of chitosan-based nanomaterials. Chitosan nanoparticles have high importance in nanomedicine, biomedical engineering, discovery and development of new drugs. The manuscript reviewed the new studies regarding ...


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