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Elevated IgA and IL-10 levels in very-early-onset inflammatory bowel disease se...

Sandy,Natascha Silva; Marega,Lia Furlaneto; Bechara,Giane Dantas; Riccetto,Adriana Gut Lopes; Bonfim,Carmen; Vilela,Maria Marluce dos Santos

ABSTRACT Objective: To report two patients with very-early-onset inflammatory bowel disease (VEOIBD) secondary to interleukin-10 receptor (IL-10R) mutations, explore immunophenotyping data and plasma cytokine profile on these cases compared to healthy controls, and describe the phenotype of IL-10/IL-10R mutations based on a literature review. Case description: We report on two female infants referred to our ter...

Date: 2022   |   Origin: Oasisbr
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