5 documents found, page 1 of 1
Chitosan/hydroxyethyl cellulose inserts for sustained-release of dorzolamide fo...
Juçara Ribeiro França; Giselle Foureaux; Leonardo Lima Fuscaldi; Tatiana Gomes Ribeiro; Rachel Oliveira Castilho; Maria Irene YoshidaCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico; FAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais; CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Eye drops containing hydrophilic drugs are commonly used to reduce intraocular pressure (IOP) in glaucoma patients, but compliance to the treatement is commonly reduced by frequent dosing and eventual systemi...
Development and chemical characterization of biodegradable polymeric implants c...
Michele Soares Tacchi Campos; Sílvia Ligório Fialho; Bruno Gonçalves Pereira; Maria Irene Yoshida; Wagner da Nova Mussel; Armando da Silva Cunha JúniorThe use of sirolimus and its analogs has been evaluated in studies aimed at combating several types of cancer; however, because of the limited bioavailability of the drug, the search for new forms of administration is required. Biodegradable polymeric implants containing sirolimus were developed and assessed as an alternative method of drug administration. Implants containing 25 % (w/w) sirolimus were prepared ...
Physics, chemistry, and hirshfeld surface analyses of gamma-irradiated thalidom...
Valner Augusto Freitas da Silva da Nova Mussel; Max Passos Ferreira; Maria Betânia de Freitas Marques; Maria Irene Yoshida; Mariana Ramos AlmeidaCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico; FAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais; CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Thalidomide was indicated as a sedative and antiemetic and prescribed for pregnant women. Its tragic teratogenic effects culminated in withdrawal from the market. Since the discovery of its anti-angiogenic an...
Kinetics of lumefantrine thermal decomposition employing isoconversional models...
Maria Betânia de Freitas Marques; Bárbara Caroline Rodrigues de Araújo; Christian Fernandes; Maria Irene Yoshida; Wagner da Nova MusselCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico; FAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais; CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Thermal analysis can be used to determine shelf-life and kinetic parameters in pharmaceutical systems. This work investigates the kinetic of lumefantrine thermal decomposition, an antimalarial, using non-isot...
Physicochemical characterization, the hirshfeld surface, and biological evaluat...
Luciana Flávia de Almeida Romani; Maria Irene Yoshida; Elionai Cassiana de Lima Gomes; Renes de Resende Machado; Felipe Fernandes RodriguesCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico; FAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais; CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Meloxicam (MLX) is an anti-inflammatory drug susceptible to variations and crystalline transitions. In compounding pharmacies, the complete crystallographic evaluation of the raw material is not a routine pro...