151 documents found, page 1 of 16
Development of a nanoformulation containing drugs with osseointegration and ant...
Luísa Melo; Maria do Carmo Pereira; Ferraz, MP; Joana A Loureiro
Development and Validation of a Simple UV-HPLC Method to Quantify the Memantine...
Débora Nunes; Tânia Tavares; Francisco Xavier Malcata; Joana A. Loureiro; Maria do Carmo PereiraMemantine, a non-competitive NMDA receptor antagonist, is used to treat Alzheimer's disease. Therefore, loading memantine in nanoparticles (NPs) could be an essential tool to improve the treatment effectiveness while reducing drug toxicity. Even though some approaches have been described to quantify memantine, none reported optimized methods using high-performance liquid chromatography resorting to ultraviolet ...
Folic-Acid-conjugated poly (Lactic-Co-Glycolic Acid) nanoparticles loaded with ...
Maria Ramalho; Bruna Alves; Stephanie Andrade; Jorge Lima; Joana A Loureiro; Maria do Carmo Pereira
A small TAT-TrkB peptide prevents BDNF receptor cleavage and restores synaptic ...
João Fonseca-Gomes; Tiago Costa-Coelho; Mafalda Ferreira-Manso; Sara Inteiro-Olvieira; Maria Ramalho; Joana A Loureiro; Maria do Carmo Pereira
Repurposing gemcitabine for glioblastoma treatment: The role of drug-conjugates...
Maria Ramalho; Érica Serra; Joana A Loureiro; Maria do Carmo Pereira
Could encapsulation of natural compounds in BBB-permeable nanocarriers produce ...
Maria Ramalho; Stephanie Andrade; Joana A Loureiro; Maria do Carmo Pereira
Indoor air quality in public schools - Preliminary results and progress of EDC(...
C. Peixoto; A.M. Faria; G. Harlem; M. Pinto; J. Madureira; J.P. Teixeira; Maria do Carmo Pereira; Klara Slezakova
Chitosan-PLGA mucoadhesive nanoparticles for gemcitabine repurposing for gliobl...
Maria Ramalho; Érica Serra; Jorge Lima; Joana A Loureiro; Maria do Carmo Pereira
Indoor Air Quality at Portuguese Firehouses
Klara Slezakova; Esteves F.; Vaz J; Costa S.; Alves M.J.; Madureira J.; Barros B.; Fernandes A.; Teixeira J.P.; Morais S.; Maria do Carmo PereiraThis work assessed firefighters exposure to gases pollutants in non- fire work settings during the pre-fire season as a baseline for the respective occupational exposure characterization. Indoor air sampling (total volatile organic compoundsTVOCs, ozone-O3, and carbon di oxide-CO2) was conducted for two weeks in the pre-fire season of 2021 in seven firehouses (FH1FH7) situated in the north-interior of Portugal....
Caffeic acid loaded into engineered lipid nanoparticles for Alzheimer's disease...
Stephanie Andrade; Maria do Carmo Pereira; Joana A LoureiroAlzheimer's disease (AD) is an incurable neurological illness and the leading cause of dementia, characterized by amyloid β (Aβ) fibril deposits. Caffeic acid (CA) has demonstrated potential value for AD therapy due to its antiamyloidogenic, anti-inflammatory, and antioxidant properties. However, its chemical instability and limited bioavailability limit its therapeutic potential in vivo. Herein, liposomes load...