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Resveratrol affords protection against peroxynitrite-mediated endothelial cell ...
Brito, Paula M.; Mariano, Anabela; Almeida, Leonor M.; Dinis, Teresa C. P.Atherosclerosis, the main cause of cardiovascular disease (CD), is a chronic inflammatory condition associated with an overproduction of oxidant species, namely peroxynitrite, which is a powerful oxidant that reacts directly with all biomolecules. Glutathione is an efficient scavenger of peroxynitrite, so, modulation of glutathione synthesis may provide a strategy to selectively protect cells from this oxidant....
Date: 2006
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Origin: Estudo Geral - Universidade de Coimbra