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Strontium ranelate analgesia in arthritis models is associated to decreased cyt...

Nunes, Rodolfo de Melo; Martins, Morgana Ramos; Silva Junior, Francisco Saraiva da; Leite, Ana Caroline Rocha de Melo; Girão, Virgínia Cláudia Carneiro

Objective We investigated the anti-inflammatory activity of strontium ranelate (SR) in arthritis models. Materials and methods Rats received 1 mg zymosan (Zy) or saline intra-articularly. Other groups were subjected to anterior cruciate ligament transection in the right knee, as an osteoarthritis (OA) model, or a sham procedure. Joint pain was assessed using the articular incapacitation and paw-pressure tests. ...

Date: 2016   |   Origin: Oasisbr

Vitamin D levels in juvenile idiopathic arthritis from an equatorial region

Studart, Sâmia Araújo de Sousa; Leite, Ana Caroline Rocha de Melo; Marinho, Aryana Lushese Lima Feitosa; Pinto, Ana Carolina Matias Dinelly

We aimed to describe the serum levels of 25-hydroxyvitamin D (25OHD) in juvenile idiopathic arthritis (JIA) patients living in a low-latitude (3°43′S) region. Fifty JIA patients, 31 (62 %) female, seen between May 2012 and April 2013 in the northeast of Brazil had clinical data and serum collected for determination of 25OHD and parathyroid hormone (PTH) using a chemiluminescent ELISA; 20 age- and sex-matched co...

Date: 2015   |   Origin: Oasisbr

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