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Hepatic steatosis and patients with inflammatory bowel disease: when transient ...

Arieira, Cátia; Monteiro, Sara; Xavier, Sofia; Dias de Castro, Francisca; Magalhães, Joana; Moreira, Maria J.; Marinho, Carla

Recent studies suggest an increased prevalence of hepatic steatosis (HS) in patients with inflammatory bowel disease (IBD). Features such as chronic inflammation, previous surgeries, drug-induced hepatotoxicity, malnutrition, and intestinal dysbiosis seem to be involved in its pathogenesis. Background Recent studies suggest an increased prevalence of hepatic steatosis (HS) in patients with inflammatory bowel di...


Optimizing the Risk Assessment in Upper Gastrointestinal Bleeding: Comparison o...

Cúrdia Gonçalves, Tiago; Barbosa, Mara; Xavier, Sofia; Boal Carvalho, Pedro; Firmino Machado, João; Magalhães, Joana; Marinho, Carla

Although different scores have been suggested to predict outcomes in the setting of upper gastrointestinal bleeding (UGIB), few comparative studies between simplified versions of older scores and recent scores have been published. We aimed to evaluate the accuracy of pre- (PreRS) and postendoscopic Rockall scores (PostRS), the Glasgow-Blatchford score (GBS) and its simplified version (sGBS), as well as the AIMS...


Strangulated Spiegel's hernia mimicking ischaemic colitis: endoscopic diagnosis...

Cúrdia Gonçalves, Tiago; Monteiro, Sara; Marinho, Carla; Cotter, José Almeida Berkeley


Acute diverticulitis and subsequent colonoscopy: instigating an old discussion

Gonçalves, Tiago Cúrdia; Barbosa, Mara; Marinho, Carla; Cotter, José Almeida Berkeley


Minimal Hepatic Encephalopathy: The Reality Beyond Our Eyes

Barbosa, Mara; Marinho, Carla; Mota, Paula; Cotter, José

Introduction: Minimal hepatic encephalopathy refers to a mild neurocognitive impairment not detectable by clinical examination that can be present in cirrhotic patients.Aim: To determine the prevalence of minimal hepatic encephalopathy in a secondary healthcare center in Northern Portugal.Material and Methods: A cross-sectional study was conducted. Cirrhotic outpatients were included. Exclusion criteria: overt ...

Date: 2015   |   Origin: Acta Médica Portuguesa

Germline MUTYH (MYH) mutations in portuguese individuals with multiple colorect...

Isidro, Glória; Laranjeira, Francisco; Pires, Ana; Leite, Júlio; Regateiro, Fernando; Sousa, F. Castro; Soares, José; Castro, Clara; Giria, João

Germinal mutations in the base excision repair (BER) gene MUTYH (MYH) have recently been described in association with predisposition to multiple colorectal adenomas and cancer. In contrast to the classic dominant condition of familial adenomatous polyposis (FAP) due to germinal mutations in the APC gene, the MYH polyposis is an autosomal recessive disease. The identification of individuals affected by MYH poly...


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