4 documents found, page 1 of 1
MALDI-TOF mass spectrometry of saliva samples as a prognostic tool for COVID-19
Lazari, Lucas C.; Zerbinati, Rodrigo M.; Rosa-Fernandes, Livia; Santiago, Veronica Feijoli; Rosa, Klaise F.; Angeli, Claudia B.; Schwab, GabrielaMade available in DSpace on 2022-05-01T15:13:36Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-01; Background: The SARS-CoV-2 infections are still imposing a great public health challenge despite the recent developments in vaccines and therapy. Searching for diagnostic and prognostic methods that are fast, low-cost and accurate are essential for disease control and patient recovery. The MALDI-TOF mas...
VEGF promotes malaria-associated acute lung injury in mice
Epiphanio, Sabrina; Campos, Marta G.; Pamplona, Ana; Carapau, Daniel; Pena, Ana C.; Ataíde, Ricardo; Monteiro, Carla A. A.; Félix, NunoThe spectrum of the clinical presentation and severity of malaria infections is broad, ranging from uncomplicated febrile illness to severe forms of disease such as cerebral malaria (CM), acute lung injury (ALI), acute respiratory distress syndrome (ARDS), pregnancy-associated malaria (PAM) or severe anemia (SA). Rodent models that mimic human CM, PAM and SA syndromes have been established. Here, we show that D...
Recrudescent Plasmodium berghei from Pregnant Mice Displays Enhanced Binding to...
Marinho, Claudio R. F.; Neres, Rita; Epiphanio, Sabrina; Goncalves, Ligia A.; Catarino, Manuela Beirao; Penha-Goncalves, CarlosPregnancy-associated malaria (PAM) is associated with placenta pathology and poor pregnancy outcome but the mechanisms that control the malaria parasite expansion in pregnancy are still poorly understood and not amenable for study in human subjects. Here, we used a set of new tools to re-visit an experimental mouse model of pregnancy-induced malaria recrudescence, BALB/c with chronic Plasmodium berghei infectio...
Pregnancy Outcome and Placenta Pathology in Plasmodium berghei ANKA Infected Mi...
Neres, Rita; Marinho, Claudio R. F.; Goncalves, Ligia A.; Catarino, Manuela Beirao; Penha-Goncalves, CarlosPregnancy-associated malaria (PAM) is expressed in a range of clinical complications that include increased disease severity in pregnant women, decreased fetal viability, intra-uterine growth retardation, low birth weight and infant mortality. The physiopathology of malaria in pregnancy is difficult to scrutinize and attempts were made in the past to use animal models for pregnancy malaria studies. Here, we des...