O projeto Via Verde Saúde Laranjeiro (VVL) foi criado em fevereiro de 2020 com o principal objetivo de prestar cuidados de saúde primários de qualidade aos cerca de 7.000 utentes inscritos na Unidade de Cuidados de Saúde Personalizados Santo António e Laranjeiro (UCSP SAL) sem equipa de família atribuída e aos cerca de 2.000 utentes esporádicos, em situação irregular, contribuindo para minorar a gritante desigu...
Leishmania infantum, a zoonotic vector-born parasite, is endemic in the Mediterranean region, presenting mostly as visceral (VL), but also as cutaneous (CL) and mucosal leishmaniasis (ML). This study aimed to describe the epidemiological and clinical aspects of the CL and ML cases diagnosed in mainland Portugal between 2010 and 2020. Collaboration was requested from every hospital of the Portuguese National Hea...
Introduction Squamous cell carcinoma of the head and neck (SCCHN) is a multifactorial disease involving genetic and environmental factors representing one of the most frequent cancer-related deaths worldwide. Tobacco and alcohol use account for most SCCHN, while a growing subset of oropharyngeal cancers is causally associated with human papillomavirus (HPV) infection. Despite improvements in overall survival, p...
Obesity is an increasing public health issue around the world. Lifestyle counselling is one of the core competencies of family doctors and can contribute to the prevention, control, and counteract of chronic disease complications. The paucity of resources in primary care practices makes an adequate response challenging. Therefore, a group of health professionals from a primary care public Family Health Unit man...
In the current pandemic times for SARS-CoV-2, several challenges are posed to the scientific community. With regard to the implementation of treatments for the elderly with cancer, despite the high complexity in its approach, a variable (SARS-CoV-2) now appears that represents a high impact on multidisciplinary decision-making processes when deciding which therapeutic strategies to use. In accordance with vario...
Background: Obesity-related comorbidities are present in young obese children, providing a platform for early adult cardiovascular disorders. Objectives: To compare and correlate markers of adiposity to metabolic disturbances, vascular and cardiac morphology in a European pediatric obese cohort. Methods: We carried out an observational and transversal analysis in a cohort consisting of 121 obese children of bot...
Introduction: Pediatric obesity is increasingly prevalent in the Portuguese population. Adipocyte dysfunction results in the expression of pro-inflammatory mediators that are responsible for the low-grade inflammatory process that characterizes obesity. Objectives: The aim of this study was to investigate the relationship between markers of adiposity, inflammation and adipokines in a Portuguese obese pediatric ...
Introdução: Rotavírus (RV) e norovírus (NoV) são descritos como causa importante de gastrenterite aguda (GEA) na criança, os últimos particularmente em surtos. Os dados nacionais sobre NoV são e escassos. Este estudo pretende determinar o papel destes vírus na etiologia da GEA num Serviço de Urgência (SU) pediátrico. Material e métodos: Estudo prospectivo dos casos de GEA observados entre janeiro e maio de 2009...
Drosophila Decapentaplegic (Dpp), a member of the BMP2/4 class of the TGF-βs, is required for organ growth, patterning and differentiation. However, much remains to be understood about the mechanisms acting downstream of these multiple roles. Here we investigate this issue during the development of the Drosophila eye. We have previously identified viriato (vito) as a dMyc-target gene encoding a nucleolar protei...