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Evaluation of the p-AKT, p-JNK and FoxO3a function in the oral epithelial dyspl...

Chaves, Filipe Nobre; Marinho, Thâmara Manoela Bezerra; Silva, Paulo Goberlânio de Barros; Oliveira, Francisco Artur Forte; Sousa, Fabrício Bitu

OBJECTIVES: To evaluate the expression of p-AKT, p-JNK, FoxO3a and KI-67 in samples of Oral Squamous Cell Carcinoma (OSCC) and Oral Epithelial Dysplasias (OEDs) to understand their possible involvement in the malignant transformation process of oral lesions. MATERIALS AND METHODS: Tissue samples of 20 cases of OSCCs, 20 OEDs and normal oral mucosa were subjected to immunohistochemistry reactions for anti-p-Akt,...

Date: 2017   |   Origin: Oasisbr

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