Enniatins (ENNs) and beauvericin (BEA) are cyclic hexadepsipeptide fungal metabolites which have demonstrated antibiotic, antimycotic, and insecticidal activities. The substantial toxic potentials of these mycotoxins are associated with their ionophoric molecular properties and relatively high lipophilicities. ENNs occur extensively in grain and grain-derived products and are considered a food safety issue by t...
Mycotoxins are secondary metabolites of fungi that may contaminate food and feed, e.g., cereals, (dried) fruits and spices. As they are natural substances, there are no manufacturers or suppliers responsible for providing hazard data, in contrast to e.g. industrial chemicals or pesticides. Humans are widely exposed to mycotoxins mainly through diet and, due to climate changes, the human exposure to these toxins...
Fungi of the genus Alternaria are ubiquitous plant pathogens and saprophytes which are able to grow under varying temperature and moisture conditions as well as on a large range of substrates. A spectrum of structurally diverse secondary metabolites with toxic potential has been identified, but occurrence and relative proportion of the different metabolites in complex mixtures depend on strain, substrate, and g...