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The impact on productivity costs of reducing unemployment in patients with adva...

Vasconcelos de Matos, L; Borges, M; Oliveira, AT; Bulhosa, C; Miguel, LS; Fidalgo de Freitas, T; Cunha, R; Mendes, AD; Arede, AJ; Marques, C; Costa, DA

This study aimed to characterize the employment status and work-related conditions of patients with advanced breast cancer (ABC) in Portugal and quantify the productivity costs of premature abandonment of the work market while evaluating strategies to promote employment. The analysis was based on a cumulative incidence model for estimation of ABC prevalence and on a cross-sectional study characterizing the empl...

Date: 2025   |   Origin: Saúde - CUF

Advancing Access to Intestinal Microbiota Transplant: Bridging the Gap Between ...

Dinis, L; Pinheiro, H; Póvoa, P; Calhau, C; Pestana, D; Marques, C

Clostridioides difficile is an opportunistic pathogen that can cause a range of conditions, from asymptomatic carriage to severe illness, posing a significant public health threat due to its high mortality rates and substantial healthcare costs. Traditional treatment options, including antibiotics, often fail to eradicate the infection, leading to recurrent cases that severely impact patients' lives. Intestinal...

Date: 2025   |   Origin: Hospital de Cascais

Bragg Gratings in ZEONEX Microstructured Polymer Optical Fiber With 266-nm Nd:Y...

Pereira, L; Marques, C; Min, R; Woyessa, G; Bang, O; Humberto Varum; Antunes, PFD

We present the first fiber Bragg gratings (FBGs) inscription in ZEONEX-480R microstructured polymer optical fiber (POF) by employing the fourth harmonic (266 nm) of a Nd:YAG laser system. The gratings were produced in the L-band region by the phase mask method, in 270-mu m diameter POF samples connectorized with ferrule connectors (FCs). The results of three produced gratings are reported, showing good stabilit...


Interrogation Method with Temperature Compensation Using Ultra-Short Fiber Brag...

Pereira, L; Min, R; Woyessa, G; Bang, O; Marques, C; Humberto Varum; Antunes, P

The use of simpler and less bulky equipment, with a reliable performance and at relative low cost is increasingly important when assembling sensing configurations for a wide variety of applications. Based on this concept, this paper proposes a simple, efficient and relative low-cost fiber Bragg grating (FBG) interrogation solution using ultra-short FBGs (USFBGs) as edge filters. USFBGs with different lengths an...


The impact of Hafnia alvei HA4597™ on weight loss and glycaemic control after b...

Ismael, S; Vaz, C; Durao, C; Silvestre, MP; Calhau, C; Teixeira, D; Marques, C

Background Subjects with obesity exhibit changes in gut microbiota composition and function (i.e. dysbiosis) that contribute to metabolic dysfunction, including appetite impairment. Although bariatric surgery is an effective treatment for obesity with a great impact on weight loss, some subjects show weight regain due to increased energy intake after the surgery. This surgery involves gut microbiota changes tha...


Changes in Microbiota Profile in the Proximal Remnant Intestine in Infants Unde...

Barreiros-Mota, I; R. Araújo, J; Marques, C; Sousa, L; Morais, J; Castela, I; Faria, A; Neto, MT; Cordeiro-Ferreira, G; Virella, D; Pita, A

Early-life gut dysbiosis has been associated with an increased risk of inflammatory, metabolic, and immune diseases later in life. Data on gut microbiota changes in infants undergoing intestinal surgery requiring enterostomy are scarce. This prospective cohort study examined the enterostomy effluent of 29 infants who underwent intestinal surgery due to congenital malformations of the gastrointestinal tract, nec...


Impact of inbreeding on growth and development of young open-pollinated progeny...

Faia, J; Costa, J; Araújo, J; Borralho, N; Marques, C; Trindade, Helena

The use of open-pollinated seeds from seed orchards is a common strategy for the deployment of genetically improved eucalypts, including Eucalyptus globulus, an important pulpwood tree in many temperate climate areas. However, seed quality can be affected by the rate of selfing and to a lesser extent by contamination from pollen outside the orchard. Inbreeding between related parents and especially from self-cr...


Depression Among Portuguese Pregnant Women During Covid-19 Lockdown: A Cross Se...

Padez Vieira, F; Mesquita Reis, J; Figueiredo, PR; Lopes, P; Nascimento, MJ; Marques, C; Caldeira da Silva, P

Introduction: Coronavirus disease 2019 was declared as a pandemic on March 2020. Research on its psychological effects is still lacking. Perinatal depression is a medical complication of pregnancy, especially in situations of stress. In this study, we aimed to investigate the presence of symptoms of depression in pregnant women during the lockdown period in Portugal. Methods: This study consisted in a cross-sec...


Patterns of Parental Reactions to Their Children’s Negative Emotions: A Cluster...

Pereira, AI; Santos, C; Barros, L; Roberto, MS; Rato, J; Prata, A; Marques, C

Parents' emotion socialization practices are an important source of influence in the development of children's emotional competencies This study examined parental reactions to child negative emotions in a clinical sample using a cluster analysis approach and explored the associations between clusters of parents' reactions and children's and parents' adjustment. The sample comprised 80 parents of Portuguese chil...


Gut Microbiota Diversity and C-Reactive Protein Are Predictors of Disease Sever...

Moreira-Rosário, A; Marques, C; Pinheiro, H; Araújo, JR; Ribeiro, P; Rocha, R; Mota, I; Pestana, D; Ribeiro, R; Pereira, A; Sousa, MJ; Pereira-Leal, J

The risk factors for coronavirus disease 2019 (COVID-19) severity are still poorly understood. Considering the pivotal role of the gut microbiota on host immune and inflammatory functions, we investigated the association between changes in the gut microbiota composition and the clinical severity of COVID-19. We conducted a multicenter cross-sectional study prospectively enrolling 115 COVID-19 patients categoriz...


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