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Combined low-carbohydrate diet and long-term exercise in hypoxia in type 2 diab...

Kindlovits, R; Sousa, AC; Viana, JL; Milheiro, J; Marques, F; Teixeira, Vitor Hugo

<jats:p> Background: Cardiovascular disease is the leading cause of mortality associated with diabetes, which is characterized by chronic hyperglycemia. Low-carbohydrate diet has gained popularity as an intervention in patients with type 2 diabetes mellitus, acting to improve glycemic profile and serum lipids. In its turn, exercise in hypoxia induces specific adaptations, mostly modulated via hypoxia-induced tr...


Forecasting COVID-19 Severity by Intelligent Optical Fingerprinting of Blood Sa...

Faria, SP; Carpinteiro, C; Pinto, V; Rodrigues, SM; Alves, J; Marques, F; Lourenço, M; Santos, PH; Ramos, A; Cardoso, MJ; Guimarães, JT; Rocha, S

Forecasting COVID-19 disease severity is key to supporting clinical decision making and assisting resource allocation, particularly in intensive care units (ICUs). Here, we investigated the utility of time- and frequency-related features of the backscattered signal of serum patient samples to predict COVID-19 disease severity immediately after diagnosis. ICU admission was the primary outcome used to define dise...


A 2018 overview of diuretic resistance in heart failure

Jardim, S; Ramos dos Santos, L; Araújo, I; Marques, F; Branco, P; Gaspar, A; Fonseca, C

Abstract Heart failure is a disease with high direct and indirect costs. Current treatment includes drugs that alter disease progression and drugs that to improve symptoms. Loop diuretics are the cornerstone of congestion relief for acute management, as well as for chronic stabilization. In heart failure patients, maximal diuretic response is reduced by many individual factors. Diuretic resistance is defined as...


Impacto das Infeções Respiratórias Viricas Múltiplas na Evolução de Crianças Gr...

Verdelho Andrade, J; Bota, S; Marques, F; Casimiro, A; Estrada, J; Santos, M

Introdução: As infecções respiratórias baixas são a principal causa de mortalidade em crianças até aos 5 anos. A utilização do painel rápido multiplex por PCR melhora a identificação do diagnóstico etiológico. Objetivos: Comparar a evolução de infecções respiratórias víricas com um ou mais agente isolado em crianças admitidas por insuficiência respiratória aguda (IRA) em cuidados intensivos. Métodos: Estudo ret...


A 2018 Overview of Diuretic Resistance in Heart Failure

Jardim, SI; Ramos dos Santos, L; Araújo, I; Marques, F; Branco, P; Gaspar, A; Fonseca, C

Heart failure is a disease with high direct and indirect costs. Current treatment includes drugs that alter disease progression and drugs that to improve symptoms. Loop diuretics are the cornerstone of congestion relief for acute management, as well as for chronic stabilization. In heart failure patients, maximal diuretic response is reduced by many individual factors. Diuretic resistance is defined as failure ...


Early detection and personalized treatment in oral cancer: the impact of omics ...

Ribeiro, IP; Barroso, L; Marques, F; Melo, JB; Carreira, IM

BACKGROUND: Oral cancer is one of the most common malignant lesions of the head and neck. This cancer is an aggressive and lethal disease with no significant improvements in the overall survival in the last decades. Moreover, the incidence of oral HPV-positive tumors is rising, especially in young people. This oral neoplasm develops through numerous molecular imbalances that affect key genes and signaling pathw...


Treatment planning systems dosimetry auditing project in Portugal

Lopes, MC; Cavaco, A; Jacob, K; Madureira, L; Germano, S; Faustino, S; Lencart, J; Trindade, M; Vale, J; Batel, V; Sousa, M; Bernardo, A; Brás, S

BACKGROUND AND PURPOSE: The Medical Physics Division of the Portuguese Physics Society (DFM_SPF) in collaboration with the IAEA, carried out a national auditing project in radiotherapy, between September 2011 and April 2012. The objective of this audit was to ensure the optimal usage of treatment planning systems. The national results are presented in this paper. MATERIAL AND METHODS: The audit methodology simu...

Date: 2014   |   Origin: Saúde - CUF

Treatment planning systems dosimetry auditing project in Portugal

Lopes, MC; Cavaco, A; Jacob, K; Madureira, L; Germano, S; Faustino, S; Lencart, J; Trindade, M; Vale, J; Batel, V; Sousa, M; Bernardo, A; Brás, S

BACKGROUND AND PURPOSE: The Medical Physics Division of the Portuguese Physics Society (DFM_SPF) in collaboration with the IAEA, carried out a national auditing project in radiotherapy, between September 2011 and April 2012. The objective of this audit was to ensure the optimal usage of treatment planning systems. The national results are presented in this paper. MATERIAL AND METHODS: The audit methodology simu...


Autism Spectrum Disorder Secondary to Enterovirus Encephalitis

Marques, F; Brito, MJ; Conde, M; Pinto, M; Moreira, A

Millions of children are infected by enteroviruses each year, usually exhibiting only mild symptoms. Nevertheless, these viruses are also associated with severe and life-threatening infections, such as meningitis and encephalitis. We describe a 32-month-old patient with enteroviral encephalitis confirmed by polymerase chain reaction in cerebrospinal fluid, with unfavorable clinical course with marked developmen...


Mastoidite Aguda em Idade Pediátrica – Fatores de Risco para Complicações

Marques, F; Vaz Silva, I; Branco, C; Paiva, M; Cunha, F

Introdução: A mastoidite aguda (MA) é a complicação mais frequente da otite média aguda (OMA). A antibioticoterapia (AB) e a melhoria dos cuidados de saúde diminuíram drasticamente a sua incidência. Porém, na última década assistiu -se ao recrudescimento da doença. Objetivos: Avaliar características sociodemográficas, clínicas, laboratoriais e terapêuticas da MA e identificar fatores de risco para complicações ...


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