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Kinetics of radium-223 and its effects on survival, proliferation and DNA damag...

Marques, IA; Abrantes, AM; Pires, AS; Neves, AR; Caramelo, FJ; Rodrigues, T; Matafome, P; Tavares-da-Silva, E; Gonçalves, AC; Pereira, CC; Teixeira, JP

Background Metastatic castration-resistant prostate cancer (mCRPC) is associated with a very unfavorable prognosis. At this advanced stage of the disease, there are several therapeutic strategies approved in recent times, being one of them Radium-223 dichloride (Radium-223). However, its mechanisms of action and the process that conducts to cell death are not fully understood. Given this, our main goal is to ch...

Date: 2021   |   Origin: Repositório Aberto da Universidade do Porto
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Array-comparative genomic hybridization as a novel high-throughput approach in ...

Neves, AR; Abrantes, AM; Ribeiro, IP; Marques, IA; Marques, V; Tavares da Silva, E; Carreira, IM; Figueiredo, A; Botelho, MF

Date: 2018   |   Origin: Repositório do Centro Hospitalar e Universitário de Coimbra
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