12 documents found, page 1 of 2
Open-Air Cold Plasma Device Leads to Selective Tumor Cell Cytotoxicity
Almeida-Ferreira, Catarina; Silva-Teixeira, Rafael; Laranjo, Mafalda; Almeida, Nuno; Brites, Gonçalo; Dias-Ferreira, João; Marques, Inês A.; Neves, RitaThe need for effective and safe therapies for cancer is growing as aging is modifying its epidemiology. Cold atmospheric plasma (CAP) has gained attention as a potential anti-tumor therapy. CAP is a gas with enough energy to ionize a significant fraction of its constituent particles, forming equal numbers of positive ions and electrons. Timely-resolved output voltage measurement, emission spectroscopy, and quan...
Cold Atmospheric Plasma, a Novel Approach against Bladder Cancer, with Higher S...
Silva, Edgar Tavares da; Pereira, Eurico; Pires, Ana S.; Neves, Ana Rita M.; Guilherme, Catarina Braz; Marques, Inês A.; Abrantes, Ana M.Antitumor therapies based on Cold Atmospheric Plasma (CAP) are an emerging medical field. In this work, we evaluated CAP effects on bladder cancer. Two bladder cancer cell lines were used, HT-1376 (stage III) and TCCSUP (stage IV). Cell proliferation assays were performed evaluating metabolic activity (MTT assay) and protein content (SRB assay). Cell viability, cell cycle, and mitochondrial membrane potential (...
Cold atmospheric plasma, a novel approach against bladder cancer, with higher s...
Tavares-da-Silva, Edgar; Pereira, Eurico; Pires, Ana S.; Neves, Ana R.; Braz-Guilherme, Catarina; Marques, Inês A.; Abrantes, Ana M; Gonçalves, Ana C.Antitumor therapies based on Cold Atmospheric Plasma (CAP) are an emerging medical field. In this work, we evaluated CAP effects on bladder cancer. Two bladder cancer cell lines were used, HT-1376 (stage III) and TCCSUP (stage IV). Cell proliferation assays were performed evaluating metabolic activity (MTT assay) and protein content (SRB assay). Cell viability, cell cycle, and mitochondrial membrane potential (...
Flushing em cateteres venosos periféricos: um protocolo de scoping review
Parreira, Pedro; Marques, Inês A.; Santos-Costa, Paulo; Sousa, Liliana; Braga, Luciene; Apóstolo, João; Salgueiro-Oliveira, AnabelaContexto: O flushing dos cateteres venosos periféricos (CVPs), aquando da administração intravenosa, encontra-se descrito como um procedimento preventivo das complicações associadas aos CVPs. Contudo, esta prática não se escontra convenientemente operacionalizada nas diretrizes internacionais em termos do volume da solução de flushing, frequência e técnica. Objetivos: Mapear as evidências no âmbito do flushing ...
Double-chamber syringe versus classic syringes for peripheral intravenous drug ...
Parreira, Pedro; Sousa, Liliana B.; Marques, Inês A.; Santos-Costa, Paulo; Braga, Luciene M.; Cruz, Arménio; Salgueiro-Oliveira, AnabelaBackground:The prevention of catheter-related complications is nowadays an important topic of research.Flushing catheters is considered an important clinical procedure in preventing malfunction and several complications such as phlebitis or infection. Considering the latest guidelines of the Infusion Nurses Society, theflushing should be carried out both pre- and post-drug administration, requiring different sy...
Usability Assessment of an Innovative Device in Infusion Therapy: A Mix-Method ...
Parreira, Pedro; Sousa, Liliana B.; Marques, Inês A.; Santos-Costa, Paulo; Cortez, Sara; Carneiro, Filipa; Cruz, Arménio; Salgueiro-Oliveira, AnabelaBackground: Flushing a venous access device is an important procedure to maintain their patency and prevent malfunctioning and complications. An innovative double-chamber syringe was developed, allowing for the assessment of catheter patency, drug delivery and final flush. This study aims to assess the usability of this new device, considering three development stages (concept, semi-functional prototype, functi...
Brief Report on Double-Chamber Syringes Patents and Implications for Infusion T...
Sousa, Liliana B.; Santos-Costa, Paulo; Marques, Inês A.; Cruz, Arménio; Salgueiro-Oliveira, Anabela; Parreira, PedroThis review aimed to map the existing patents of double-chamber syringes that can be used for intravenous drug administration and catheter flush. A search was conducted in the Google patents database for records published prior to 28 October 2020, using several search terms related to double-chamber syringes (DCS). Study eligibility and data extraction were performed by two independent reviewers. Of the initial...
Study Protocol for Two-Steps Parallel Randomized Controlled Trial: Pre-Clinical...
Parreira, Pedro; Sousa, Liliana B.; Marques, Inês A.; Santos-Costa, Paulo; Cortez, Sara; Carneiro, Filipa; Cruz, Arménio; Salgueiro-Oliveira, AnabelaA new double-chamber syringe (DUO Syringe) was developed for intravenous drug administration and catheter flushing. This study presents a protocol for pre-clinical usability tests to validate the golden prototype of this new device, performed in a high-fidelity simulation lab by nurses. A two-steps parallel randomized controlled trial with two arms was designed (with standard syringes currently used in clinical...
Development of an innovative double-chamber syringe for intravenous therapeutic...
Parreira, Pedro; Sousa, Liliana B.; Marques, Inês A.; Costa, Paulo; Cortez, Sara; Carneiro, Filipa; Cruz, Arménio; Salgueiro-Oliveira, AnabelaIn nursing practice, flushing the catheters pre and post-drug administration is considered an important clinical procedure to prevent complications, and requires the use of several syringes to comply with international standards of care. We envisioned an innovative double-chamber syringe that enables the filling and administration of both solutions. Following current international recommendations, the developme...
Brief report on double-chamber syringes patents and implications for infusion t...
Sousa, Liliana B.; Santos-Costa, Paulo; Marques, Inês A.; Cruz, Arménio; Salgueiro-Oliveira, Anabela; Parreira, PedroThis review aimed to map the existing patents of double-chamber syringes that can be used for intravenous drug administration and catheter flush. A search was conducted in the Google patents database for records published prior to 28 October 2020, using several search terms related to double-chamber syringes (DCS). Study eligibility and data extraction were performed by two independent reviewers. Of the initial...