5 documents found, page 1 of 1
Bio-piezoelectric ceramic composites for electroactive implants—biological perf...
Fernandes, Beatriz Ferreira; Silva, Neusa; Marques, Joana Faria; Da Cruz, Mariana Brito; Tiainen, Laura Katariina; Gasik, MichaelBarium titanate (BaTiO<sub>3</sub>) piezoelectric ceramic may be a potential alternative for promoting osseointegration due to its piezoelectric properties similar to bone electric potentials generated in loading function. In this sense, the aim of this in vitro study was to evaluate the cellular response of human osteoblasts and gingival fibroblasts as well as the impact on <i>S. oralis</i> when in contact wit...
Modification of Zirconia implant surfaces by Nd:YAG laser grooves: does it chan...
da Cruz, Mariana Brito; Marques, Joana Faria; Marques, Ana Filipa Silva; Madeira, Sara; Carvalho, Óscar; Silva, Filipe Samuel; Caramês, JoãoThe aim of this study was to evaluate gingival fibroblasts and human osteoblasts’ response to textured Nd:YAG laser microgrooves, with different dimensions, on zirconia implant surfaces. A total of 60 zirconia disks (8 mm in diameter and 2 mm in thickness) were produced and divided between four study groups (N = 15): three laser-textured (widths between 125.07 ± 5.29 μm and 45.36 ± 2.37 μm and depth values from...
Human gingival fibroblast and osteoblast behavior on groove-milled zirconia imp...
Cruz, Mariana Brito da; Marques, Joana Faria; Silva, Neusa; Madeira, Sara Cristina Soares; Carvalho, Óscar Samuel Novais; Silva, Filipe SamuelTwo type of cells representing periodontal hard tissues (osteoblasts) and soft tissues (fibroblasts) were evaluated in response to microgroove-milled zirconia surfaces. A total of 90 zirconia discs were randomly assigned to four width-standardized milling microgroove-textured groups and a control group without grooves (UT). The sandblast and acid-etch protocol were applied to all samples. Both cell lines were c...
Biomimetic implant surfaces and their role in biological integration—a concise ...
Cruz, Mariana Brito; Silva, Neusa; Marques, Joana Faria; Mata, António; Silva, Filipe Samuel; Caramês, JoãoBackground: The increased use of dental implants in oral rehabilitation has been followed by the development of new biomaterials as well as improvements in the performance of biomaterials already in use. This triggers the need for appropriate analytical approaches to assess the biological and, ultimately, clinical benefits of these approaches. Aims: To address the role of physical, chemical, mechanical, and bio...
Evaluation of Saliva Stability for NMR Metabolomics: Collection and Handling Pr...
Duarte, Daniela Alexandra Oliveira; Castro, Beatriz; Pereira, Joana Leonor; Marques, Joana Faria; Costa, Ana Luísa; Gil, Ana M.Maintaining a salivary metabolic profile upon sample collection and preparation is determinant in metabolomics. Nuclear magnetic resonance (NMR) spectroscopy was used to identify metabolite changes during short-term storage, at room temperature (RT)/4 °C/-20 °C, and after sample preparation, at RT/4 °C (mimicking typical clinical/laboratory settings). Interestingly, significant metabolic inter-individual and in...