Encontrados 3 documentos, a visualizar página 1 de 1
Population medical genetics: translating science to the community
Giugliani,Roberto; Bender,Fernanda; Couto,Rowena; Bochernitsan,Aline; Brusius-Facchin,Ana Carolina; Burin,Maira; Amorim,Tatiana; Acosta,Angelina XavierAbstract Rare genetic disorders are currently in the spotlight due to the elevated number of different conditions and significant total number of affected patients. The study of these disorders is extremely helpful for the elucidation of physiological processes related with complex disorders. Isolated populations are instrumental for the study of genetic disorders, considering their homogeneity and high proport...
Topical hepatic hypothermia plus ischemic preconditioning: analysis of bile flo...
Grezzana Filho,Tomaz de Jesus Maria; Mendonça,Tais Burmann de; Gabiatti,Gémerson; Rodrigues,Graziella; Marroni,Norma Anair Possa; Treis,LisianePURPOSE: To evaluate the effects of the topical liver hypothermia and IPC combination against I/R injury after initial reperfusion. METHODS: In 32 Wistar rats, partial liver ischemia was induced for 90 minutes in normothermia (IN), ischemic preconditioning (IPC), 26ºC topical hypothermia (H) and 26ºC topical hypothermia plus IPC (H+IPC). MAP, body temperature and bile flow were recorded each 15 minutes. Plasmat...
Hepatics alterations and genotoxic effects of Croton cajucara Benth (SACACA) in...
Rodrigues,Graziella; Marcolin,Éder; Bona,Silvia; Porawski,Marilene; Lehmann,Mauricio; Marroni,Norma PossaCONTEXT: Croton cajucara Benth is a plant found in Amazonia, Brazil and the bark and leaf infusions of this plant have been popularly used to treat diabetes and hepatic disorders. OBJECTIVES: This study investigated effects hepatics alterations and genotoxic and antidiabetic effect of Croton cajucara Benth bark extracts treatment in streptozotocin-induced diabetic rats. METHODS: Male Wistar rats were divided in...