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Epidemiological aspects of human visceral Leishmaniasis in the State of Piauí, ...

Ferreira, Henrique Rafael Pontes; Pacheco, Ana Carolina Landim; Marques, Márcia Maria Mendes

Background: Visceral leishmaniasis presents considerable expansion in urban centers in state of Piauí, its occurrence is marked by successive records of outbreaks. Objective: to analyze the reported cases of human visceral leishmaniasis in Piauí, between the years 2007 to 2017. Methods: The data were obtained from Notifiable Diseases Information System (Sinan-Datasus), variables were analyzed according to the S...

Date: 2021   |   Origin: Oasisbr

Evaluación de la citotoxicidad, genotoxicidad y toxicidad subcrónica de diéster...

Canabrava, Natália do Vale; Silva, Jose Ytalo Gomes da; Silva, Bruno Bezerra da; Holanda, Marcelo Oliveira; Lima, Carla Laine Silva

P-methoxycinnamic diesters from carnauba wax powder (PCO - C) – cinnamic acid derivate – have been associated with new properties such as hypolipidemic, hypocholesterolemic and hypoglycaemic effects in mice. The present study aimed to investigate the safety profile of PCO - C by evaluating the subchronic oral toxicity, genotoxicity and mutagenicity using in vivo experimental models. Therefore, for the present r...

Date: 2020   |   Origin: Oasisbr

Cytotoxic and genotoxic potential of industrialized powdered milk for infants a...

Silva, Geysa Janne Sousa; Santos, Fabelina Karollyne Silva dos; Marques, Márcia Maria Mendes; Peron, Ana Paula

This study aimed to evaluate the cytotoxicity and genotoxicity and determine the LC50 concentration of powdered infant formulas widely marketed in South American countries. To this, milk samples, called as A, B, C and D, were analyzed in root meristem cells of Allium cepa, at concentrations of 0.075; 0.15 and 0.30 g mL-1, for 24 and 48 hours; and through cell viability in culture of normal line cells, via MTT t...

Date: 2020   |   Origin: Oasisbr

Toxicity of food flavorings to ex-vivo, in vitro and in vivo bioassays

Santos, Fabelina Karollyne da Silva dos; Marques, Márcia Maria Mendes; Van Tilbulrg, Maurício Fraga; Guedes, Maria Izabel Florindo

This study evaluated the toxicity of food flavorings of mint, cinnamon and lemon in meristem root cells of Allium cepa, in pure form (as marketed) and in the concentrations of 12.5, 25, and 50%, after 24 and 48 hours of exposure; in Vero cell culture evaluated by MTT test and in nauplii of Artemia salina, both tests used flavorings in pure form and in the concentrations of 0.78, 1.56, 3.12, 6.25, 12.5, 25, and ...

Date: 2019   |   Origin: Oasisbr

Antioxidant activity and physicochemical analysis of passion fruit (Passiflora ...

Lima-Neto, Abelardo Barbosa Moreira; Marques, Márcia Maria Mendes; Mendes, Francisca Noélia Pereira; Vieira, Ícaro Gusmão Pinto

The objective of this study was to determine the proximal composition, the physical and chemical characteristics and the in vitro antioxidant capacity (DPPH, ABTS and FRAP) of the pulp of the wild passion fruit (Passiflora glandulosa Cav.) from Cariri region, Ceara, Brazil. The results showed that the proximal composition and the caloric value of this passion fruit are similar to other species, but with a high ...

Date: 2017   |   Origin: Oasisbr

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