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Chemical Characterization and Differential Lipid-Modulating Effects of Selected...

Amorim, Ricardo; Marques, Mário Pedro; Melim, Catarina; Varela, Carla; Sardão, Vilma A.; Teixeira, José; Dias, Maria Inês; Barros, Lillian

Côa Valley, located in the northeast of Portugal, harbors more than 500 medicinal plant species. Among them, four species stand out due to their traditional uses: Equisetum ramosissimum Desf. (hemorrhages, urethritis, hepatitis), Rumex scutatus L. subsp. induratus (Boiss. and Reut.) Malag. (inflammation, constipation), Geranium purpureum Vill., and Geranium lucidum L. (pain relief, gastric issues). Given their ...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Essential Oils from Côa Valley Lamiaceae Species: Cytotoxicity and Antiprolifer...

Marques, Mário Pedro; Neves, Beatriz Guapo; Varela, Carla Lopes; Zuzarte, Mónica; Gonçalves, Ana Cristina; Dias, Maria Inês; Amaral, Joana S.

Lavandula pedunculata (Mill.) Cav., Mentha cervina L. and Thymus mastichina (L.) L. subsp. mastichina are representative species of the Côa Valley's flora, a Portuguese UNESCO World Heritage Site. L. pedunculata and T. mastichina are traditionally used to preserve olives and to aromatize bonfires on Saint John's Eve, while M. cervina is mainly used as a spice for river fish dishes. Despite their traditional use...


Nanotechnology-Based Topical Delivery of Natural Products for the Management of...

Marques, Mário Pedro; Varela, Carla Lopes; Mendonça, Laura; Cabral, Célia

Atopic dermatitis (AD) is a chronic eczematous inflammatory disease that may arise from environmental, genetic, and immunological factors. Despite the efficacy of current treatment options such as corticosteroids, such approaches are mainly focused on symptom relief and may present certain undesirable side effects. In recent years, isolated natural compounds, oils, mixtures, and/or extracts have gained scientif...


Côa Valley’s medicinal plants as potential cosmetic ingredients: cytotoxic and ...

Marques, Mário Pedro; Landim, Euclides; Varela, Carla; Marques, Joana; Costa, Ricardo; Carvalho, Luís de; Carvalho, Aida; Oliveira, Paulo; Cabral, Célia

Côa Valley is a Northeast region of Portugal, classified as a UNESCO World Her- itage Site since 1998, and recognised as “the most important open-air Paleo- lithic rock art site”. So far, little is known about the natural endogenous resourc- es of this territory, namely medicinal plants. According to a preliminary ethnobotanical survey in this region, several medicinal plants were mentioned to have skin-benefic...

Date: 2023   |   Origin: Biblioteca Digital do IPB

Essential oils from coa valley lamiaceae species: cytotoxicity and antiprolifer...

Marques, Mário Pedro; Neves, Beatriz Guapo; Varela, Carla; Zuzarte, Mónica; Goncalves, Ana Cristina; Dias, Maria Inês; Amaral, Joana S.; Barros, Lillian

Lavandula pedunculata (Mill.) Cav., Mentha cervina L. and Thymus mastichina (L.) L. subsp. mastichina are representative species of the Coa Valley's flora, a Portuguese UNESCO World Heritage Site. L. pedunculata and T. mastichina are traditionally used to preserve olives and to aromatize bonfires on Saint John's Eve, while M. cervina is mainly used as a spice for river fish dishes. Despite their traditional use...

Date: 2023   |   Origin: Biblioteca Digital do IPB

Côa Valley’s medicinal plants as potential cosmetic ingredients: cytotoxic and ...

Marques, Mário Pedro; Landim, Euclides; Varela, Carla; Marques, Joana; Costa, Ricardo M.F. da; Carvalho, Luís A.E. Batista de; Carvalho, Aida

Where is located and what is the importance of river Côa Valley? • The river Côa Valley is part of the Guarda District, in the Northeast of Portugal. The Valley comprises an Archeological Park, which is considered “the most important open-air Paleolithic rock art site” in the world, being classified as UNESCO World Heritage Site since 1998. What are the natural resources’ relevance of this region? • The flora o...

Date: 2023   |   Origin: Biblioteca Digital do IPB

Essential oils from Côa Valley Lamiaceae species: cytotoxicity on glioblastoma ...

Marques, Mário Pedro; Delgado, Jéssica; Zuzarte, Mónica; Varela, Carla; Dias, Maria Inês; Barros, Lillian; Magalhães, Mariana; Cabral, Célia

Lavandula pedunculata (Mill.) Cav., Mentha cervina L. and Thymus mastichina (L) L. subsp. mastichina are widely used and fairly representative species of the flora and traditional uses of the Côa Valley, a Portuguese UNESCO World Heritage Site. L. pedunculata and T. mastichina are used by local populations to preserve olives, as a condiment in traditional cuisine and to aromatize bonfires on Saint John's Eve, w...

Date: 2022   |   Origin: Biblioteca Digital do IPB

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