7 documents found, page 1 of 1
Physiotherapists’ barriers and facilitators to the implementation of a behaviou...
Moniz, A; Duarte, ST; Aguiar, P; Caeiro, C; Pires, D; Fernandes, R; Moço, D; Marques, MM; Sousa, R; Canhão, H; Branco, J; Rodrigues, AM; Cruz, EBBackground: Recurrences of low back pain (LBP) are frequent and associated with high levels of disability and medical costs. Regular exercise practice may be an effective strategy to prevent recurrences of LBP, however, the promotion of this behaviour by physiotherapists seems to be challenging. This study aims to explore physiotherapists' perceived barriers and facilitators to the implementation of a behaviour...
Endobronchial Ultrasound under Moderate Sedation versus General Anesthesia
Fernandes, MG; Santos, VF; Martins, N; Sucena, MC; Passos, MM; Marques, MM; Magalhães, AM; Bugalho, ABACKGROUND: Different anesthetic protocols may influence endobronchial ultrasound-guided needle aspiration (EBUS-TBNA) outcomes, patient comfort, and even safety. In this study, two anesthesia techniques were assessed and compared for EBUS-TBNA. METHODS: A prospective, multicenter study was carried out. Patients were allocated to Group 1 (general anesthesia with neuromuscular blockade and controlled ventilation...
Differences in Nevirapine Biotransformation as a Factor for its Sex-Dependent D...
Marinho, AT; Rodrigues, PM; Caixas, U; Antunes, A; Branco, T; Harjivan, S; Marques, MM; Monteiro, EC; Pereira, SAOBJECTIVES: Nevirapine is widely used for the treatment of HIV-1 infection; however, its chronic use has been associated with severe liver and skin toxicity. Women are at increased risk for these toxic events, but the reasons for the sex-related differences are unclear. Disparities in the biotransformation of nevirapine and the generation of toxic metabolites between men and women might be the underlying cause....
Monitoring Abacavir Bioactivation in Humans: Screening for an Aldehyde Metabolite
Grilo, N; Antunes, A; Caixas, U; Marinho, A; Charneira, C; Oliveira, MC; Monteiro, E; Marques, MM; Pereira, SThe anti-HIV drug abacavir is associated with idiosyncratic hypersensitivity reactions and cardiotoxicity. Although the mechanism underlying abacavir-toxicity is not fully understood, drug bioactivation to reactive metabolites may be involved. This work was aimed at identifying abacavir-protein adducts in the hemoglobin of HIV patients as biomarkers of abacavir bioactivation and protein modification. The protoc...
The Bucaco Basin (Portugal): Organic petrology and geochemistry study
Flores, D; Gama Pereira, LCG; Ribeiro, J; Pina, B; Marques, MM; Ribeiro, MA; Bobos, I; Pinto P de JesusThe Bucaco Basin includes a Carboniferous/Permian sequence that comprises, from bottom to top, the following stratigraphic sequence: Algeriz Formation, Vale da Mo Formation and Monsarros Formation. Algeriz Formation is constituted by deposits of basal breccia with variable thickness and alternating layers of siltstone, mudstone and conglomerate. Vale da Mo Formation corresponds to lacustrine deposits comprising...
Glycidamide-DNA adducts and sister chromatid exchanges in human lymphocytes exp...
Pingarilho, M; Martins, C; Oliveira, NG; Vaz, S; Gamboa da Costa, G; Martins, V; Marques, MM; Beland, FA; Churchwell, MI; Doerge, DR; Rueff, J
Induction of sister-chromatid exchanges and chromosomal aberrations by acrylami...
Martins, C; Gaspar, J; Martins, V; Gamboa da Costa, G; Marques, MM; Rueff, J; Oliveira, NG