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Expression of tumor suppressors miR-195 and let-7a as potential biomarkers of i...

Marques, Marcia M.; Evangelista, Adriane F.; Macedo, Taciane; Vieira, Rene Aloisio da Costa; Scapulatempo-Neto, Cristovam; Reis, Rui M.

OBJECTIVE: MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression at the posttranscriptional level. Some miRNAs, including let-7a and miR-195, have been described as tumor suppressors. However, the roles of these microRNAs in breast cancer progression remain controversial. The aim of this study is to evaluate miR-195 and let-7a expression as potential biomarkers of invasive breast cancer. ME...

Date: 2019   |   Origin: Oasisbr

Expression of tumor suppressors miR-195 and let-7a as potential biomarkers of i...

Marques, Marcia M.; Evangelista, Adriane F.; Macedo, Taciane; Vieira, René Aloisio da Costa; Scapulatempo-Neto, Cristovam; Reis, R. M.

MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression at the posttranscriptional level. Some miRNAs, including let-7a and miR-195, have been described as tumor suppressors. However, the roles of these microRNAs in breast cancer progression remain controversial. The aim of this study is to evaluate miR-195 and let-7a expression as potential biomarkers of invasive breast cancer.


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