The radish (Raphanus sativus L.) is a vegetable of the Brassicaceae family cultivated worldwide and has several medicinal properties. Its biological activities are related to various secondary metabolites present in the species, especially phenolics. Thus, the objectives of this study were the chemical analysis and evaluation of the antioxidant and antimicrobial activities of the dry extract and fractions of th...
Made available in DSpace on 2019-10-06T15:40:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-05-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG); Financiadora de Estudos e Projetos; Abstract: A new series of silver compounds could be of interes...
Neste trabalho, foi avaliado o perfil de isotipos de imunoglobulinas anti-Paracoccidioides brasiliensis em soros de pacientes com formas crônica e aguda de paracoccidiodomicoses usando antígeno total e tratado com meta-periodato. Todos os tipos de imunoglobulinas presentes nos soros de pacientes com formas aguda e crônica apresentaram alta reatividade ao antígeno total quando comparado ao tratado com meta-perio...
Introdução: O cão pode atuar como reservatório doméstico do protozoário Leishmania. Apirases (ou ATP difosfohidrolases) isoladas de formas promastigotas de {L. (L.) amazonensis} e {L. (V.) braziliensis} apresentam imunoreatividade cruzada com anticorpos anti-apirase de batata (Parasitology 135:327-335, 2008). Análises {in silico} permitiram observar uma relação evolucionária e estrutural entre a apirase de bata...
Made available in DSpace on 2016-01-28T16:56:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2012. Added 1 bitstream(s) on 2016-01-28T17:02:47Z : No. of bitstreams: 1 ISSN1517-0276-2012-10-01-49-55.pdf: 96306 bytes, checksum: 6c8c2b32ff3786a2e18658c24ef30d88 (MD5); Infections by protozoans of the genus Leishmania are the major worldwide health problem, with high endemicity in developing countries. The drug...
Made available in DSpace on 2016-01-28T16:56:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2011. Added 1 bitstream(s) on 2016-01-28T17:02:47Z : No. of bitstreams: 1 ISSN1517-0276-2011-09-01-220-238.pdf: 192426 bytes, checksum: f110411ebabe7a32ada0310e8f4956cd (MD5); Não há vacinas disponíveis contra leishmanioses. A resistências às drogas, eficácia variável, toxicidade, administração parenteral e a neces...
O presente trabalho descreve inicialmente um cão com sintomas característicos de leishmaniose visceral. Amostra de soro desse cão foi positiva por imunofluorescência indireta (IFI) conduzida no IgG total anti- Leishmania em 1999. Além disso, tecidos desse cão foram positivos por reação em cadeia pela polimerase (PCR) conduzida em 2004, identificando DNA de Leishmania no cerebelo, fígado, rim e intestino. Esta é...
Molecular analysis, serology and immunophenotyping for T lymphocytes and their subsets, B lymphocytes and monocytes were performed on dogs naturally infected with Leishmania infantum. Animals were categorised as asymptomatic dogs I (AD-I), with negative serology and positive molecular results, and asymptomatic dogs II (AD-II), with positive serology and positive molecular results, and these were compared to sym...
Zoonotic visceral leishmaniasis in Brazil is caused by Leishmania infantum parasites andis transmitted by sand flies of the Phlebotominae family. Dogs are the main urban reser-voirs and represent the major source of contagion for the vectors. Studies have shown thatmost infected dogs are polymerase chain reaction-positive months before seroconversion.Herein, we describe a cohort study designed to identify the i...
Visceral leishmaniasis (VL) has recently emerged in various urban and peri-urban areas of Brazil and other countries. Understanding the urbanization of VL requires identification of risk factors associated with human and canine infection. To determine the predictors of risk for canine VL, a survey was conducted of 1,443 dogs, from which a cohort was selected (n = 455) and evaluated for approximately 26 months. ...