Made available in DSpace on 2015-05-15T13:30:27Z (GMT). No. of bitstreams: 0 Previous issue date: 2010Bitstream added on 2015-05-15T13:56:34Z : No. of bitstreams: 1 ISSN1809-8460-2010-05-01-01-05.pdf: 62663 bytes, checksum: c59822cb60fdc88f6bc0a80d756e6205 (MD5); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); A pesquisa e o uso de plantas inseticidas têm aumentado nos últimos anos. Sua co...
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A busca por herbicidas eficientes e ambientalmente corretos tem sido foco de numerosos estudos sobre a síntese de compostos isolados de fontes naturais. Citosporonas, as quais são lipídeos fenólicos isolados de fungos, apresentam notáveis propriedades biológicas. Este artigo relata a preparação das citosporonas A, B e C, através de uma rota sintética curta e com excelentes rendimentos. Os compostos sintetizados...
ABSTRACT - Cytotoxic activity of eight plant extracts, native from the Mid-West of Brazil comprising Cerrado, Pantanal and semideciduous forest, was evaluated for MDA-MB-435, SF-295, and HCT-8 cancer cell strains. A single 100 µg.mL-1 dose of each extract was employed with 72 h of incubation for all tests. Doxorubicin (1 µg.mL-1) was used as the positive control and the MTT method was used to detect the activit...
With the aim of obtaining new compounds with potential antifungal activity, lecanoric acid, a chemical constituent of the lichen Parmotrema tinctorum and its derivatives prepared from structural modification were tested against the fungus Cladosporium sphaerospermum, by employing the bioautographic method. Activity of the derivatives ranged from 10- to 1-μg concentrations. Results demonstrated this series of co...
Inspired by the structure and biological activities of resorcinolic lipids and, particularly cytosporone A- a potent inhibitor of plantule germination and growth, we have performed the synthesis of the analogs 3-heptyl-3-hydroxy-5,7-dimethoxy-2-benzofuran-1(3H)-one (1) and 3-heptyl-3-hydroxy-4,6-dimethoxy-2-benzofuran-1(3H)-one (2). The intermediates and products were submitted to allelopathic test using Lactuc...
The sesquiterpene (+)-allo-aromadendrane-10β-14-diol 1 was the lead compound to the preparation of several derivatives in order to test their biological activity against A. salina, C. sphaerospermum, E. coli and S. aureus. In this way the monoalcohols (+)-viridiflorol 4, 9 and 11 were synthesized from 1 together with the acetal 6, the ketal 7, and the ketone 8. The oxirane 3 and nitrile 5 were also prepared usi...
The present study aimed to evaluate the ability for biotransformation of the Diels-Alder adduct tricyclo[6.2.1.02,7]undeca-4,9-dien-3,6-dione (1) and two synthetic derivatives by the saprobe fungus Mucor ramosissimus Samutsevitsch. Products from oxidation, isomerization and, regioselective and enantioselective reduction were achieved.; Neste trabalho avaliou-se a capacidade de biotransformação do aduto de Diels...
Uma das fontes efêmeras de alimento que os insetos podem utilizar são as gomas exsudadas por plantas. No mês de maio de 2005, em uma área de cerrado no município de Campo Grande, Mato Grosso do Sul, foram observados insetos visitando as estruturas de exsudação em um indivíduo de Terminalia agentea Mart & Zucc (Combretaceae). Foram registradas 19 espécies, principalmente Trigona branneri (Cockerell) e Mesembrine...