82 documents found, page 1 of 9
Laparoscopic Resection of a Perianastomotic Recurrence of Colon Adenocarcinoma ...
Vale Guimarães, André; Peyroteo, Mariana; Pinto, Paula; Marques, Mariana; Madeira-Cardoso, Maria João; Abreu de Sousa, Joaquim.; .
Duplication of the Left Gastric Artery Identified During Laparoscopic Radical S...
Marques, Mariana; Lencastre, Luís; Vale Guimarães, André; Cardoso, Maria João; Ferreira Pinto, Paula; Pereira, José Carlos; Videira, Flávio.; .
The Muslim community as a client: a narrative review of the literature
Bicho, Ana; Marques, Mariana; Guerreiro, DéboraIntroductionCulture is a person's circumstance and shapes their experience of the world and life. It is represented by patterns of behavior, with repercussions on health processes. It is a central issue when we think about nursing care centered on the person, family or community. In Portugal, immigrant communities have shown a growing and challenging trend in the provision of nursing care. Some of the main immi...
Empowerment of Educational Agents in a School Context: Scoping Review Protocol
Marques, Mariana; Guerreiro, Débora; Bicho, Ana; Xavier, SandraIntroductionChildren and adolescents with special health needs have chronic, physical and developmental conditions that impact functionality, dependence on health systems intervention and quality of life as students. These young people need an adequate response to their special health needs in a school context, a place they attend for a third of their day.1 Nurses work in various contexts throughout the life cy...
Development of an in vitro skin cell model and comparison with ex vivo models: ...
Marques, Mariana; Teixeira, Filipa; Vieira, Mónica; Rodrigues, Francisca; Vieira, MónicaSkin is the first physical barrier against pathogens and mechanical injuries, and stratum corneum, the outermost layer of the skin, is the primary barrier to therapeutic delivery. Skin is divided into the epidermis, which consists mainly of keratinocytes and the dermis, composed of fibroblasts, and extracellular matrix components. Skin models are crucial for assessing the safety and efficacy of cosmetic ingredi...
Nursing-led training of school staff to care for children and adolescents with ...
Marques, Mariana; Guerreiro, Débora; Bicho, Ana; Xavier, SandraIntroduction Children and adolescents with special health care needs (SHCN) live with chronic physical and developmental conditions that affect functioning and require ongoing support from health systems. Nurses work throughout the lifespan and across various care settings; they are well positioned to provide health education and deliver specialized care to individuals, groups, and communities, leading to impro...
Extrahepatic Lymphadenectomy in Intrahepatic Cholangiocarcinoma: Current Eviden...
Marques, MarianaLymph node metastasis (LNM) is one of the most adverse prognostic factors in intrahepatic cholangiocarcinoma (iCCA), with five-year overall survival rarely exceeding 15% in node-positive patients. The role and extent of extrahepatic lymphadenectomy in this setting, however, remain controversial. This narrative review synthesizes the current evidence on nodal assessment in iCCA, including prognostic implications...
Influenza A virus propagation requires the activation of the unfolded protein r...
Marques, Mariana; Ramos, Bruno; Albuquerque, Hélio; Pereira, Marisa; Ribeiro, Diana Roberta; Nunes, Alexandre; Sarabando, Jéssica; Brás, DanielaInfluenza A virus (IAV) employs multiple strategies to manipulate cellular mechanisms and support proper virion formation and propagation. In this study, we performed a detailed analysis of the interplay between IAV and the host cells’ proteostasis throughout the entire infectious cycle. We reveal that IAV infection activates the inositol requiring enzyme 1 (IRE1) branch of the unfolded protein response, and th...
RADIATION-INDUCED SARCOMAS: A SURGICAL CHALLENGE
Ferreira Pinto, Paula; Pereira, José Carlos; Correia, Ana Margarida; Baía, Catarina; Marques, Mariana; Silva, José; Martins, Pedro; Santos, Lúcio LaraMalignant peripheral nerve sheath tumors (MPNST) are uncommon, biologically challenging soft tissue sarcomas. The definitive treatment of these tumors is extremely challenging. In 50% of cases, these tumors are associated with type I neurofibromatosis, but in some cases, the cause can be previous treatment with radiotherapy. The present article pretends to report a clinical case of a radiation-induced MPNST sub...
Synthesis, In Vitro Biological Evaluation of Antiproliferative and Neuroprotect...
Brito, Vanessa; Marques, Mariana; Esteves, Marta; Serra-Almeida, Catarina; Alves, Gilberto; Almeida, Paulo; Bernardino, Liliana; Silvestre, SamuelSteroids constitute an important class of pharmacologically active molecules, playing key roles in human physiology. Within this group, 16E-arylideneandrostane derivatives have been reported as potent anti-cancer agents for the treatment of leukemia, breast and prostate cancers, and brain tumors. Additionally, 5α,6α-epoxycholesterol is an oxysterol with several biological activities, including regulation of cel...