2 documents found, page 1 of 1
In Vitro Models for Anti-Aging Efficacy Assessment: A Critical Update in Dermoc...
Cruz, Ana M.; Gonçalves, Margarida C.; Marques, Matilde S.; Veiga, Francisco; Paiva-Santos, Ana Cláudia; Pires, Patrícia C.The skin is the human body’s largest organ and serves as a crucial boundary between the body and the external environment. As a natural process, skin aging cannot be avoided, and it causes changes in the skin’s strength, structure, elasticity, and integrity. Many approaches have been developed over the years to study the skin, including in vivo and in vitro methods. Nevertheless, animal assays have ethical issu...
Marine Sponge and Octocoral-Associated Bacteria Show Versatile Secondary Metabo...
Almeida, João F; Marques, Matilde S.; Oliveira, Vanessa; Egas, Conceição; Mil-Homens, Dalila; Viana, Romeu; Cleary, Daniel F. R.; Huang, Yusheng MMarine microbiomes are prolific sources of bioactive natural products of potential pharmaceutical value. This study inspected two culture collections comprising 919 host-associated marine bacteria belonging to 55 genera and several thus-far unclassified lineages to identify isolates with potentially rich secondary metabolism and antimicrobial activities. Seventy representative isolates had their genomes mined f...