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Sociodemographic, Clinical, and Behavioral Factors Associated With Sexual Trans...

Miranda, M; Pimentel, V; Graça, J; Seabra, S; Sebastião, C; Diniz, A; Faria, D; Teófilo, E; Roxo, F; Maltez, F; Germano, I; Oliveira, J; Ferreira, J

Introduction: Sexually transmitted infections (STIs) continue to occur at high levels. According to the WHO, each year there are an estimated 374 million new infections with syphilis, gonorrhea, chlamydia, and trichomoniasis. STIs are associated with an increased risk of acquiring HIV infection. Migrants are reportedly highly affected by STIs. Objectives: This study aims to characterize factors associated with ...


Lessons from Four Decades of Systemic Amyloidosis with Renal Involvement

Oliveira-Silva, C; Marques, N; Pinho, A; Poínhos, Rui; Bergantim, R; Nunes, AT; Sampaio, S; Rodrigues-Pereira, P; Silva, R; Praça, A; Frazão, J

Background: Apart from ATTR amyloidosis, the epidemiology and outcomes of the most common subtypes of systemic amyloidosis in Portugal remain primarily unknown. Methods: This retrospective cohort study evaluated patients with renal biopsy-proven amyloidosis, diagnosed from January 1978 to December 2019. Follow-up started at kidney disease presentation and ended at death or August 2020. Clinical presentation, su...


Trapeziectomy with Suture-Button Suspensionplasty Versus Ligament Reconstructio...

Morais, B; Botelho, T; Marques, N; Nóbrega, J; Ferrão, A; Jorge, J; Teixeira, F

The purpose of the present study was to compare the results of patients operated with trapeziectomy and ligament reconstruction and tendon interposition (LRTI) using flexor carpi radialis tendon versus trapeziectomy followed by suspension of the first metacarpal to the second metacarpal using a Mini TightRope® suture button (suture button suspension: SBS). A single-center prospective randomized controlled trial...


HIV-1-Transmitted Drug Resistance and Transmission Clusters in Newly Diagnosed ...

Pingarilho, M; Pimentel, V; Miranda, M; Silva, AR; Diniz, A; Ascenção, B; Piñeiro, C; Koch, C; Rodrigues, C; Caldas, C; Morais, C; Faria, D

Objective: To describe and analyze transmitted drug resistance (TDR) between 2014 and 2019 in newly infected patients with HIV-1 in Portugal and to characterize its transmission networks. Methods: Clinical, socioepidemiological, and risk behavior data were collected from 820 newly diagnosed patients in Portugal between September 2014 and December 2019. The sequences obtained from drug resistance testing were us...


Is Bilateral Hallux Valgus Chevron Osteotomy a Safe Procedure for Ambulatory Su...

Morais, B; Botelho, T; Marques, N; Ferrão, A; Nóbrega, J; Teixeira, F; Grenho, A

Introduction: Several osteotomies of the first metatarsal have been described for treatment of hallux valgus but chevron osteotomy is one of the most common and well-established procedure for treating this deformity. Although there is a trend towards considering bilateral surgery there is lack of publications addressing bilateral treatment in ambulatory units. The aim of this study is to analyze results of bila...


Intraocular Lens Power Calculation Formulas Accuracy in Combined Phacovitrectom...

Hipólito-Fernandes, D; Luís, ME; Maleita, D; Gil, P; Maduro, V; Costa, L; Marques, N; Branco, J; Alves, N

Background: Our study aimed to assess and compare the accuracy of 8 intraocular lens (IOL) power calculation formulas (Barrett Universal II, EVO 2.0, Haigis, Hoffer Q, Holladay 1, Kane and PEARL-DGS) in patients submitted to combined phacovitrectomy for vitreomacular (VM) interface disorders. Methods: Retrospective chart review study including axial-length matched patients submitted to phacoemulsification alone...


Validation of the Ottawa Ankle Rules: Strategies for Increasing Specificity

Morais, B; Branquinho, A; Barreira, M; Correia, J; Machado, M; Marques, N; Ferrão, A; Nóbrega, J; Teixeira, F; Diogo, N

Introduction: The majority of patients with ankle injuries undergo radiological examinations of the foot, ankle or both. The objective of this study was in the first place to validate the Ottawa Ankle Rules (OARs) for the population of our centre. Secondly, an attempt was made to identify parameters that contribute to improve the specificity of the method, with a view to reduce the need for patients to be expos...


Circulating renalase as predictor of renal and cardiovascular outcomes in pre-d...

Cerqueira, A; Quelhas-Santos, J; Ferreira, I; Sampaio, S; Relvas, M; Marques, N; Dias, CC; Pestana, M

Chronic kidney disease (CKD) is an independent risk factor for adverse cardiovascular and cerebrovascular events (MACCEs), and mortality since the earlier stages. Therefore, it is critical to identify the link between CKD and cardiovascular risk (CVR) through early and reliable biomarkers. Acknowledging that CKD and CKD progression are associated with increased sympathetic tone, which is implicated in CVR, and ...


Visceral dissemination of mucocutaneous leishmaniasis in a kidney transplant re...

Marques, N; Bustorff, M; Cordeiro-da-Silva, A; Pinto, AI; Santarém, N; Ferreira, F; Nunes, A; Cerqueira, A; Rocha, A; Ferreira, I; Tavares, I; Santos, J

Intracellular protozoan of the genus Leishmania, endemic in the Mediterranean basin, are the cause of cutaneous (CL), mucocutaneous (MCL), and visceral leishmaniasis (VL). A 75-year-old woman was admitted nine years after a second kidney transplant (KT), due to persistent pancytopenia and fever. She presented edema and erythema of the nose in the last two years and an exophytic nodular lesion located on the lef...


Endothelial dysfunction is associated with cerebrovascular events in pre-dialys...

Cerqueira, A; Quelhas-Santos, J; Sampaio, S; Ferreira, I; Relvas, M; Marques, N; Dias, CC; Pestana, M

Background: Patients with chronic kidney disease (CKD) have markedly increased rates of end stage renal disease, major adverse cardiovascular/cerebrovascular events (MACCEs), and mortality. Endothelial dysfunction (ED) is an early marker of atherosclerosis that is emerging as an increasingly important non-traditional cardiovascular risk factor in CKD. There is a lack of clinical studies examining the associatio...


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