34 documents found, page 1 of 4
Tunneled Interpolated Flaps in the Reconstruction of Nasal Defects
Bonito, Frederico; Pinho, André; Brinca, Ana; Goulão, João; Vieira, RicardoThe reconstruction of nasal skin defects is a challenge even for an experienced dermatological surgeon. When the defect is too large or complex to be corrected with simpler flaps, interpolated flaps are a good option, but they usually require two surgeries. Tunneled interpolated flaps were developed to allow the reconstruction of complex defects in only one surgical procedure. In nasal reconstruction, the main ...
Treatment of BRAF-Mutated Metastatic Melanoma: Immunotherapy or Target Therapy?
Rodrigues, Ana Sofia; Brinca, AnaMetastatic melanoma has been associated with a poor prognosis, with overall survival rates at 5 years of 10%. Until 2011, the only treatments available for metastatic melanoma were chemotherapy and immunotherapy with interleukin-2. The more in-depth knowledge about the molecular biology of melanoma and the identification of BRAF mutations, which are the most frequently found, allowed us to find new therapeutic ...
Reconstruction of a Major Facial Defect with Multiple Z-Plasty Dermatologic Sur...
Batista, Mariana; Santiago, Luís; Pinho, André; Brinca, Ana; Vieira, RicardoZ-plasty is a surgical technique classically used to correct scars. It consists of a double transposition of two or more adjacent triangular-shaped flaps resulting in a Z-shaped scar. This procedure is especially advantageous when the surgical incision is not parallel to the skin tension lines as it allows repositioning of the tension vectors, tending to a more favorable cosmetic result and preventing scar retr...
Advanced Merkel Cell Carcinoma: A New Case of Spontaneous Regression
Guiote, Victoria; Cunha, Fernanda; Pinho, André; Brinca, Ana; Vieira, RicardoMerkel cell carcinoma is an aggressive skin neoplasm affecting predominantly older or immunosuppressed patients. The progression to metastatic disease is frequent while spontaneous regression is quite uncommon. Chronic sun exposure and infection by Merkel cell polyomavirus are known etiopathogenic factors. An 89-year-old female was observed with a locally advanced Merkel cell carcinoma of the left nasal ala. Ly...
Reparo da pálpebra inferior por fechamento direto com cantopexia lateral e elev...
Vieira, Ricardo; Pinho, André; Brinca, AnaOs defeitos cutâneos da pálpebra inferior frequentemente requerem reconstruções com enxertos ou retalhos para evitar-se o ectrópio. A retirada de um carcinoma basocelular da pálpebra inferior de uma paciente de 39 anos resultou em um defeito exclusivamente cutâneo, com diâmetros transversal e vertical de 32 e 13mm, respectivamente. Apesar da grande dimensão do defeito, a elevação da fáscia suborbicular dos olho...
Gorlin-Goltz Syndrome: Diagnosis and Treatment Options
Mendes-Abreu, João; Pinto-Gouveia, Miguel; Tavares-Ferreira, Cátia; Brinca, Ana; Vieira, RicardoThe Gorlin-Goltz syndrome is a rare autosomal dominant hereditary condition, with complete penetrance and variable expressivity. Characterized by the appearance of multiple basaliomas, and often the development of keratocyst, it can also express itself by the presence of palmar/plantar depressions, calcification of brain sickle, and skeletal birth defects, although less frequently. This article presents two cas...
Síndrome de Gorlin-Goltz: Diagnóstico e hipóteses de tratamento
Mendes-Abreu, João; Pinto-Gouveia, Miguel; Tavares-Ferreira, Cátia; Brinca, Ana; Vieira, RicardoA síndrome de Gorlin-Goltz é uma patologia hereditária, rara, autossómica dominante de penetrância completa, com expressividade variável. Caracterizada pelo aparecimento de múltiplos basaliomas, cursa, frequentemente, com o desenvolvimento de queratoquistos. Depressões palmares/plantares, calcificações da foice cerebral, anomalias esqueléticas congénitas, constituem, igualmente, critérios de diagnóstico, embora...
Umbilicus Reconstruction After Melanoma Excision
Costa-Silva, Miguel; Ferreira, Bárbara; Brinca, Ana; Vieira, RicardoAn 81-year-old woman was admitted with a nodular cutaneous melanoma of the abdominal wall involving the umbilicus. After performing wide excision with 2 cm margin of the melanoma, umbilical reconstruction and defect closure were planned. After careful consideration, we decided to use an island pedicle flap which allowed closure of the defect and reconstruction of the umbilicus.
ANTIPLATELET AND ANTICOAGULANT THERAPY IN DERMATOLOGICAL SURGERY – CLINICAL PRA...
Brinca, Ana; Pinto Gouveia, Miguel; Vieira, RicardoIntroduction: Management of antithrombotic therapy is not a consensual topic in the field of dermatologic surgery. Skin surgeons must weigh the risk of bleeding against the thrombotic risk when deciding how to manage those drugs in the perioperative setting. Material and Methods: The authors reviewed the literature in order to provide clinical practice guidelines for the management of these patients.Results: Th...
ATYPICAL FIBROXANTHOMA – RARE TUMOR ARISING IN A BURN SCAR
Gameiro, Ana; Gouveia, Miguel; Brinca, Ana; Cardoso, José Carlos; Vieira, RicardoAtypical fibroxanthoma (AFX) is a relatively rare cutaneous tumor, characteristically presenting as a rapidly growing solitary nodule in photo-exposed areas of elderly patients. In spite of worrisome histological features, like pleomorphism and high mitotic rate, prognosis is favorable. Case report: A 62-year-old woman, with cicatricial alopecia on the parietal area, secondary to a thermal burn in her childhood...