11 documents found, page 1 of 2
Automated manufacturing of three-dimensional cell matrices with nanofibres of c...
Completo, A.; Marques, P. A. A. P.This invention relates to a system and a process for the automated manufacture of three-dimensional cell matrices by electrospinning from nanofibres of controlled alignment and uniform cell distribution throughout their thickness. From the implementation of the invention it is possible to obtain, in a totally automatic way and without manual intervention, three-dimensional cell matrices of aligned polymeric fib...
Development of a DoE with a new electrospinning system for cartilage tissue eng...
Silva, E.; Semitela, A.; Marques, P. A. A. P.; Completo, A.Electrospinning is currently one of the most used techniques to produce fibrous synthetic tissues such as cartilage and bone. To replicate cartilage tissue engineering functionality, one of the most important characteristics is the alignment of the resulting fibre meshes in a three-dimensional (3D) fashion. Here, a newly developed electrospinning collector system is tested in order to understand how the process...
Automated fabrication of 3D chondrocyte-laden anisotropic scaffolds for articul...
Semitela, Â.; Pereira, A. L.; Capitão, A.; Mendes, A. F.; Marques, P. A. A. P.; Completo, A.Tissue engineering (TE) strategies for repairing and regenerating articular car-tilage face critical challenges to approximate the biochemical and biomechanical microen-vironment of native tissue, particularly regarding collagen fibril depth-orientation and chondrocyte distribution. Here, a recently developed electromechanically 3D electrospin-ning platform was employed to develop three-dimensional (3D) anisotr...
Multi–layered electrospinning and electrospraying approach: effect of polymeric...
Semitela, A.; Pereira, A.; Sousa, C.; Mendes, A. F.; Marques, P. A. A. P.; Completo, A.Articular cartilage was expected to be one of the first tissues to be successfully engineered, but replicating the complex fibril architecture and the cellular distribution of the native cartilage has proven difficult. While electrospinning has been widely used to reproduce the depth–dependent fibre architecture in 3D scaffolds, the chondrocyte-controlled distribution remains an unsolved problem. To incorporate...
Fabricação automática de matrizes celulares tridimensionais com nanofibras de a...
Completo, A.; Marques, P. A. A. P.A presente invenção diz respeito a sistema e processo de fabrico automático de matrizes celulares tridimensionais com nanofibras de alinhamento controlado e distribuição celular uniforme ao longo da espessura. O sistema da presente invenção compreende um módulo de formação de nanofibras por eletrofiação, um modulo coletor das nanofibras constituído por dois cilindros coletores (6,30), um módulo de deposição das...
Electrospinning system and process for large scale manufacturing of aligned 3D ...
Completo, A.; Marques, P. A. A. P.This invention relates to the system and process of continuous electrospinning for the production of three-dimensional matrices of aligned polymeric fibres. The system of the present invention comprises an electrospinning capillary tube (3) with positive polarity, a set of multi-electrodes with negative polarity inserted in a peripheral support (15), having each electrode (7) controlled movement allowing its ex...
Self-assembled diphenylalanine peptide microtubes covered by reduced graphene o...
Ivanov, M. S.; Khomchenko, V. A.; Salimian, M.; Nikitin, T.; Kopyl, S.; Buryakov, A. M.; Mishina, E. D.; Salehli, F.; Marques, P. A. A. P.
TiO2/graphene and TiO2/graphene oxide nanocomposites for photocatalytic applica...
Martins, Pedro M.; Ferreira, C. G.; Silva, A. R.; Magalhães, B.; Alves, M. M.; Pereira, Luciana; Marques, P. A. A. P.; Melle-Franco, M.This work reports a computational study, focused on graphene (G) and graphene oxide (GO) interfaces with titanium dioxide (TiO2), and an experimental assay on the photocatalytic activity of TiO2/G and TiO2/GO nanocomposites in the degradation of two different pollutants: methylene blue and ciprofloxacin. Both carbon nanostructures were compared due to their different chemical structure: GO is a G derivative wit...
Sistema e processo de fabricação em larga escala de matrizes tridimensionais de...
Completo, A.; Marques, P. A. A. P.A presente invenção diz respeito a sistema e processo de eletrofiação em contínuo para produção de matrizes tridimensionais de fibras poliméricas alinhadas. O sistema da presente invenção compreende um tubo capilar de eletrofiação (3) com polaridade positiva, um conjunto de multi elétrodos com polaridade negativa inseridos num suporte periférico (15), tendo cada elétrodo (7) movimento controlado permitindo a su...
Phase change materials and carbon nanostructures for thermal energy storage: a ...
Amaral, C.; Vicente, R.; Marques, P. A. A. P.; Barros-Timmons, A.The high thermal conductivity of carbon based nanostructures (CNs) has been recognized appropriate to be integrated into phase change materials (PCMs) to enhance the overall thermal properties of the obtained nanocomposites. The equilibrium of the possibility to enhance the thermal conductivity of the PCMs and the latent heat capcity are the key for their ability to store or dissipate a large amount of energy i...