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Menstrual cycle among adolescents: girls' awareness and influence of age at men...

Marques, Patricia; Madeira, Tiago; Gama, Augusta

Objective: To characterize the menstrual cycle (regularity and menstrual flow length), the prevalence of dysmenorrhea and selfmonitoring of the cycle in students from Lisbon region, and explore the effect of chronological age, age at menarche and body mass index (BMI) on menstrual disorders. Methods: This is a cross-sectional study with 848 girls aged 12–18 years. A questionnaire about the sociodemographic cont...


Excesso de peso ou obesidade e fatores do estilo de vida em idosos do concelho ...

Gama, Augusta; Marques, Patricia; Madeira, Tiago; Marques, Vítor Rosado

Pretendeu caracterizar-se o estado nutricional de idosos por avaliação de indicadores antropométricos e conhecer o papel de fatores socioeconómicos e de estilos de vida no excesso de peso, incluindo obesidade (ExP+Ob), e obesidade abdominal. Desenvolveu- se um estudo transversal em instituições de Lisboa (Portugal) e a amostra estudada foi de 434 pessoas com idade igual ou superior a 60 anos. A maioria dos part...


Evaluation of the potential association of SOHLH2 polymorphisms with non-obstru...

Sánchez, Maria I.S.; Martín, Miriam C.; Egea, Rocío R.; Puchalt, Nicolás G.; Marco, Saturnino L.; Magraner, Gema R.; Ribeiro, Samuel

Non-obstructive azoospermia (NOA) or spermatogenic failure is a complex disease with an important genetic component that causes infertility in men. Known genetic factors associated with NOA include AZF microdeletions of the Y chromosome or karyotype abnormalities; however, most causes of NOA are idiopathic. During the last decade, a large list of associations between single-nucleotide polymorphisms (SNP) and NO...


Adaptive evolution and divergence of SERPINB3: a young duplicate in great Apes

Gomes, Silvia; Marques, Patricia; Matthiesen, Rune; Seixas, Susana

A series of duplication events led to an expansion of clade B Serine Protease Inhibitors (SERPIN), currently displaying a large repertoire of functions in vertebrates. Accordingly, the recent duplicates SERPINB3 and B4 located in human 18q21.3 SERPIN cluster control the activity of different cysteine and serine proteases, respectively. Here, we aim to assess SERPINB3 and B4 coevolution with their target proteas...


Radiografia Torácica em Crise Asmática

Sanches, Marcos; Marques, Patricia; Oliveira, Elisabete; Lopes, Aldina Canteiro

Criança de oito anos, asmática que iniciou de forma súbita opressão torácica, disfagia e cansaço, motivo pelo qual recorreu ao serviço de urgência. Ao exame físico apresentava tiragem intercostal, polipneia e edema supraclavicular à direita crepitante. A auscultação pulmonar revelava murmúrio vesicular diminuído bilateralmente, aumento do tempo expiratório com sibilos dispersos. A radiografia (Rx) de tórax demo...


THE EFFECT OF LIPOPOLYSACCHARIDE PRECONDITIONING IN AN EXPERIMENTAL MODEL OF BU...

Marques, Patricia; Rocha, Joao; Pinto, Rui; Sepodes, Bruno; Thiemermann, Christoph; Mota-Filipe, Helder


THE EFFECT OF SIMVASTATTN PRE-TREATMENT IN AN EXPERIMENTAL MODEL OF BURN INJURY...

Marques, Patricia; Rocha, Joao; Pinto, Rui; Sepodes, Bruno; Thiemermann, Christoph; Mota-Filipe, Helder


Inhibition of endogenous hydrogen sulphide formation protects the liver from sc...

Sepodes, Bruno; Rocha, Joao; Marques, Patricia; Pinto, Rui; Thiemermann, Christoph; Mota-Filipe, Helder


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