46 documents found, page 1 of 5

Effect of Diosgenin in Suppressing Viability and Promoting Apoptosis of Human P...

Diosgenin is a phytosteroid sapogenin with reported antitumoral activity. Despite the evidence indicating a lower incidence of prostate cancer (PCa) associated with a higher consumption of phytosteroids and the beneficial role of these compounds, only a few studies have investigated the effects of diosgenin in PCa, and its mechanisms of action remain to be disclosed. The present study investigated the effect of...

Trapped Lung from Calcified Fibrothorax

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THYROID AUTO-IMMUNITY AS A RISK FACTOR FOR RECURRENT MULTINODULAR GOITER AFTER ...

Background. The ideal surgical strategy to multinodular goiter (MNG) is currently still matter of discussion. Thyroid auto- immunity is a well-known risk factor for hypothyroidism and could play a role in MNG’s physiopathology. Objective. Assess thyroid auto-immunity as a risk factor for MNG recurrence. Materials and Methods. Retrospective analysis of a 5-year (January 2012 – December 2016) prospective dat...

Interactive VPL-based global illumination on the GPU using fuzzy clustering

Physically-based synthesis of high quality imagery, including global illumination light transport phenomena, results in a significant workload, which makes interactive rendering a very challenging task. We propose a VPL-based ray tracing approach that runs entirely in the GPU and achieves interactive frame rates while handling global illumination light transport phenomena. This approach is based on clustering b...

A Change of Paradigm for the Design and Reliability Testing of Touch-Based Cabi...

The current design paradigm of car cabin components assumes seats aligned with the driving direction. All passengers are aligned with the driver that, until recently, was the only element in charge of controlling the vehicle. The new paradigm of self-driving cars eliminates several of those requirements, releasing the driver from control duties and creating new opportunities for entertaining the passengers duri...

Cancer cell metabolism: Rewiring the mitochondrial hub

To adapt to tumoral environment conditions or even to escape chemotherapy, cells rapidly reprogram their metabolism to handle adversities and survive. Given the rapid rise of studies uncovering novel insights and therapeutic opportunities based on the role of mitochondria in tumor metabolic programing and therapeutics, this review summarizes most significant developments in the field. Taking in mind the key rol...

SmartPlastic: Innovative Touch-Based Human-Vehicle Interface Sensors for the Au...

Environmental concern regularly leads to the study and improvement of manufacturing processes and the development of new industrial products. The purpose of this work is to optimize the amount of injected plastic and reduce the number of parts used in the production of entrance panels to control features inside the car cabin. It focuses on a particular case study, namely the control of opening and closing windo...

FOAM is the Concept: Medicine in the 21st Century?

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P-cadherin induces anoikis-resistance of matrix-detached breast cancer cells by...

Successful metastatic spreading relies on cancer cells with stem-like properties, glycolytic metabolism and increased antioxidant protection, allowing them to escape anoikis and to survive in circulation. The expression of P-cadherin, a poor prognostic factor in breast cancer, is associated with hypoxic, glycolytic and acidosis biomarkers. In agreement, P-cadherin-enriched breast cancer cell populations present...

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