4 documents found, page 1 of 1
In vitro and in silico evaluation of the schistosomicidal activity of eugenol d...
Souza,Isabella Maria Monteiro de; Novaes,Romulo Dias; Gonçalves,Reggiani Vilela; Fialho,Felipe Leonardo Bley; Carvalho,Diogo TeixeiraAbstract Background Eugenol shows both antibacterial and antiparasitic activities, suggesting that it might be evaluated as an option for the treatment of praziquantel-resistant schistosome. Methods The in vitro activities of three eugenol derivatives (FB1, FB4 and FB9) on adult worms from Schistosoma mansoni were examined by fluorescence and scanning electron microscopy to analyze effects on the excretory syst...
Autochthonous canine visceral leishmaniasis in a non-endemic area: Bom Sucesso,...
Silva,Marcio Roberto; Marques,Marcos José; Romanha,Alvaro José; Santa-Rosa,Idael Christiano de Almeida; Carneiro,Cláudia M.; Reis,Alexandre BarbosaThe article begins by describing a dog with characteristic symptoms of visceral leishmaniasis. A serum sample from this animal was positive by indirect immunofluorescence (IIF) performed in anti-Leishmania total IgG in 1999. Tissues from the same dog were also positive by polymerase chain reaction (PCR) in 2004, identifying Leishmania DNA in the cerebellum, liver, kidney, and intestine. This is the first report...
Human serum antibody reactivity towards Paracoccidioides brasiliensis antigens ...
Ferreira,Ana Paula; Côrrea,Thadeu; Cunha,Rosângela; Marques,Marcos José; Montesano,Maria Angela; Souza,Maria Aparecida; Teixeira,Henrique CoutoIn this study, we evaluated the profile of anti-Paracoccidioides brasiliensis immunoglobulin isotypes in serum from patients with the acute and chronic forms of paracoccidioidomycosis, using the whole Paracoccidioides brasiliensis antigen and the antigen treated with sodium metaperiodate. All the immunoglobulin isotypes present in the serum from patients with the acute and chronic forms of paracoccidioidomycosi...
Anticorpos antipromastigotas vivas de Leishmania (Viannia) braziliensis, detect...
Rocha,Roberta Dias Rodrigues; Gontijo,Célia Maria Ferreira; Elói-Santos,Silvana Maria; Carvalho,Andréa Teixeira; Corrêa-Oliveira,RodrigoNeste estudo, descrevemos etapas iniciais de padronização de uma nova metodologia para detecção de anticorpos antipromastigotas vivas de Leishmania (Viannia) braziliensis, pela citometria de fluxo e a análise de sua aplicabilidade para estudos clínicos. Foram avaliados 39 indivíduos com sorologia convencional (RIFI) positiva para leishmaniose, classificados quanto à ausência/presença de lesão (L- e L+). Os resu...