3 documents found, page 1 of 1
Atividade anticolinesterásica e perfil químico de uma fração cromatográfica ati...
Marques,Thiago Henrique Costa; Santos,Pauline Sousa dos; Freitas,Rivelilson Mendes de; Carvalho,Rusbene Bruno Fonseca de; Melo,Cassio Herbert Santos deThis work describes the isolation of an active flavonoid fraction and identification of isorhamnetin 3-O-β-D-(6''-acetyl)-galactopyranoside from flowers of B. perennis, and also the evaluation of anticholinesterase (AChE) activity of ethanolic extract from flowers (EEF) and the active fraction. The chemical structure of the flavonoid was defined on the basis of spectroscopic ¹H NMR, IR and UV data. EEF or flavo...
Chemical composition and anxiolytic-like effects of the Bauhinia platypetala
Santos,Francisco José Borges dos; Lima,Sidney Gonçalo de; Cerqueira,Gilberto S.; Citó,Antônia Maria das Graças LopesThe pantropical genus Bauhinia, Fabaceae, known popularly as cow's foot, is widely used in folk medicine as antidiabetic. Behavioral effects of the ethanolic extract and ethereal, aqueous and ethyl acetate fractions from B. platypetala Benth. ex Hemsl. leaves were studied in male Swiss mice. The ethanolic extract and fractions were administered intraperitoneally and its effects on spontaneous motor activity (to...
In vitro evaluation of antioxidant, anxiolytic and antidepressant-like effects ...
Marques,Thiago Henrique Costa; Melo,Cássio Herbert Santos de; Freitas,Rivelilson Mendes deAcute toxicity, antioxidant activity in vitro and general pharmacological effects of the flower crude ethanolic extract of Bellis perennis L., Asteraceae, a popular medicine used in South America, were investigated in mice. The oral route LD50 value was found 2.31 g/kg. Oral administration at doses 50, 100 and 150 mg/kg of the extract neither caused significant changes in general behavior nor led to toxic sympt...