2 documents found, page 1 of 1
Biosimilars in oncology.
Barroso, Sérgio; Coutinho, Jorge; Damasceno, Margarida; Dinis, José; Forjaz de Lacerda, João; Gervásio, Helena; Leal da Costa, FernandoThe development of biotechnology drugs represents one of the great advances in medical therapy and it was observed an exponential growth in its use. The resource to these drugs in Oncology and Hematology is no exception and it soon became an essential element of an integrated and directed therapy strategy. The expiry of the first biotechnology drugs patents has opened the door for the development and marketing ...
Use of granulocyte growth factors: recommendations of the Portuguese Society of...
Forjaz de Lacerda, João; Leal da Costa, Fernando; Marques Pereira, Ana; Príncipe, Fernando; Teixeira, Adriana; Parreira, AntónioThe administration of cytotoxic chemotherapy may be complicated by the emergence of neutropenia and febrile neutropenia, frequently determining hospital admission and intravenous treatment with broad spectrum antibiotics. Frequently, it is necessary to reduce the dose or to delay the administration of the cytotoxic drugs reducing the relative dose intensity of the chemotherapy regimen. Granulocyte growth factor...