2 documents found, page 1 of 1
HERVs establish a distinct molecular subtype in stage II/III colorectal cancer ...
Golkaram, Mahdi; Salmans, Michael L.; Kaplan, Shannon; Vijayaraghavan, Raakhee; Martins, Marta; Khan, Nafeesa; Garbutt, Cassandra; Wise, AaronColorectal cancer (CRC) is one of the most lethal malignancies. The extreme heterogeneity in survival rate is driving the need for new prognostic biomarkers. Human endogenous retroviruses (hERVs) have been suggested to influence tumor progression, oncogenesis and elicit an immune response. We examined multiple next-generation sequencing (NGS)-derived biomarkers in 114 CRC patients with paired whole-exome and wh...
Hospital Protocol for Snakebite Victims Management
Marques da Costa, Pedro; Sousa, Rodrigo; Lobo Antunes, Maria; Azevedo, Sara; Araújo e Sá, Gabriela; Machado, Maria do CéuVenomous snakebites are relatively rare in Portugal. Pediatric victims present with greater severity and are at risk of fatal complications. Clinical management protocols are the gold standard of care worldwide. We report two cases of venomous adder bites in pediatric patients. Based on a literature review we also discuss the clinical management and present a treatment protocol that ensures multidisciplinary an...