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Wearable Devices for Physical Activity and Healthcare Monitoring in Elderly Peo...

Teixeira, E; Fonseca, H; Diniz-Sousa, F; Veras, L; Boppre, G; Oliveira, J; Pinto, D; Alves, AJ; Barbosa, A; Mendes, R; Marques-Aleixo, I

The availability of wearable devices (WDs) to collect biometric information and their use during activities of daily living is significantly increasing in the general population. These small electronic devices, which record fitness and health-related outcomes, have been broadly utilized in industries such as medicine, healthcare, and fitness. Since they are simple to use and progressively cheaper, they have als...


Physical exercise positively modulates DOX-induced hepatic oxidative stress, mi...

Santos-Alves, E; Rizo-Roca, D; Marques-Aleixo, I; Coxito, P; Martins, S; Guimarães, JT; Oliveira, PJ; Torrella, J; Magalhães, J; Ascensão, A

Doxorubicin (DOX), a widely used and efficient antineoplastic agent, is mainly limited by cardiotoxicity, although other tissues including liver are also affected. The effects of exercise to cope with DOX side-effects has already been studied in the heart and brain, demonstrating successful results. However, the benefits of this non pharmacological strategy have not been so extensively checked in the liver. We ...


Exercise mitigates diclofenac-induced liver mitochondrial dysfunction

Santos-Alves, E; Marques-Aleixo, I; Coxito, P; Balça, MM; Rizo-Roca, D; Rocha-Rodrigues, S; Martins, S; Torrella, JR; Oliveira, PJ; Moreno, AJ

Background: Several strategies have been developed to counteract liver injury as a consequence of nonsteroid anti-inflammatory drugs toxicity. Here, we aimed to determine whether physical exercise results in liver mitochondrial protection against in vitro diclofenac toxicity. Material and methods: Male adult Sprague-Dawley rats were divided into sedentary, 12-week endurance training (ET) and voluntary activity ...


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