1 document found, page 1 of 1
Sort by
Issue Date
New 8-hydroxyquinoline derivatives as promising therapeutic approaches targetin...
Marques-Oliveira , R.; Alfenim, A. R.; Soares , P.; Borges , F.; Remião, F.; Fernandes, C.; Silva , R.Background: Alzheimer's disease, Parkinson's disease, and Amyotrophic lateral sclerosis are recognized as the most prevalent neurodegenerative diseases (NDs), presenting a huge burden for society. These diseases share common pathophysiological mechanisms, such oxidative stress, dysfunction in iron metabolism, ferroptosis, and protein misfolding [1-4]. Given their powerful metal chelating and antioxidant propert...
Date: 2023
|
Origin: Scientific Letters