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Modified cellulose nanocrystals encapsulating cannabigerol: a step forward in c...

Casanova, Francisca; Pereira, Carla F.; Ribeiro, Alessandra B.; Castro, Pedro M.; Martins, Eva; Freixo, Ricardo; Tavares-Valente, Diana

Cannabigerol (CBG) from Cannabis sativa L. is known for its anti-inflammatory, antibacterial, and antioxidant properties, showing potential against intestinal inflammation. However, its lipophilic nature limits its absorption and stability. Researchers have explored cellulose nanocrystals (CNCs) to deliver lipophilic compounds and enhance their biological outcomes. This study investigated the capability of modi...


In situ milk enrichment with microbial CLA/CLNA using vegetable oils as substra...

Fontes, Ana L.; Pimentel, Lígia L.; Domingues, M. Rosário; Rodríguez-Alcalá, Luis M.; Gomes, Ana M.


Stability of a lyophilized milk enriched with microbial CLA/CLNA

Fontes, Ana L.; Pimentel, Lígia L.; Rodríguez-Alcalá, Luis M.; Gomes, Ana M.


Stability of a fermented milk enriched with microbial CLA/CLNA

Fontes, Ana L.; Pimentel, Lígia L.; Rodríguez-Alcalá, Luis M.; Gomes, Ana M.

There is an increasing interest towards the development of innovative value-added food products with a potential to prevent or counteract disease conditions, many times impelled by unbalanced diets, such as cardiovascular diseases and cancer. Several promising food-derived lipids with potential bioactive properties have been identified over the last decade, and these include conjugated linoleic (CLA) and conjug...


Influence of shaking and viable cell numbers on microbial conjugated linoleic a...

Fontes, Ana L.; Pimentel, Lígia L.; Salsinha, Ana S.; Rodríguez, Juan M.; Domingues, M. Rosário; Rodríguez-Alcalá, Luis M.; Gomes, Ana M.


Microbial production of conjugated linoleic acid and conjugated linolenic acid ...

Salsinha, Ana S.; Pimentel, Lígia L.; Fontes, Ana L.; Gomes, Ana M.; Rodríguez-Alcalá, Luis M.

Conjugated linoleic acids (CLAs) and conjugated linolenic acids (CLNAs) have gained significant attention due to their anticarcinogenic and lipid/energy metabolism-modulatory effects. However, their concentration in foodstuffs is insufficient for any therapeutic application to be implemented. From a biotechnological standpoint, microbial production of these conjugated fatty acids (CFAs) has been explored as an ...



Evidences and perspectives in the utilization of CLNA isomers as bioactive comp...

Fontes, Ana L.; Pimentel, Lígia; Simões, Catarina D.; Gomes, Ana M. P.; Rodríguez-Alcalá, Luís M.

Conjugated linolenic acid (CLNA) isomers are promising lipids due to their similarities with CLA but exerting their bioactivity at lower doses; some isomers also belong to the omega 3 family. This review aims to summarize the state of the art about the utilization of CLNA as a functional ingredient. Indeed, in vitro and in vivo studies reported that CLNA exerted anti-cancer, anti-inflammatory, anti-obese and an...


Considerations about the in situ derivatization and fractionation of EFA and NE...

Pimentel, Lígia L.; Fontes, Ana L.; Gomes, Ana M.; Rodríguez-Alcala, Luis M.

Despite their important role in tissues, fluids and foods, the analysis of non-esterified fatty acids (NEFA) asmethyl esters (NEFAME) is performed using expensive, cumbersome and time-consuming procedures that needs of isolation, fractionation and derivatization steps. However, Yi et al. [1] proposed a promising in situ, single-step procedure to analyze esterified fatty acids (EFA) and NEFA from a same sample o...


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