3 documents found, page 1 of 1
National survey of the rat hepatitis E virus in rodents in Spain, 2022 to 2023
Caballero-Gómez, J; Fajardo-Alonso, T; Ríos-Muñoz, L; Beato-Benítez, A; Casares-Jiménez, M; García-Bocanegra, I; Cuadrado-Matías, R; Martí-Marco, ABackgroundRat hepatitis E virus (ratHEV) is an emerging virus causing acute and chronic hepatitis in humans. Rats are the main natural reservoir of this pathogen. Large-scale studies assessing ratHEV circulation in rodents in Spain are lacking.AimWe aimed to determine the prevalence of ratHEV in rats in Spain and evaluate potential transmission risk to humans.MethodsWe designed a cross-sectional nationwide stud...
The neuronal S100B protein is a calcium-tuned suppressor of amyloid- aggregation
Cristóvão, J; Morris, V; Cardoso, I; Leal, S; Martínez, J; Botelho, H; Göbl, C; David, R; Kierdorf, K; Alemi, M; Madl, T; Fritz, G; Reif, B; Gomes, CAmyloid-β (Aβ) aggregation and neuroinflammation are consistent features in Alzheimer’s disease (AD) and strong candidates for the initiation of neurodegeneration. S100B is one of the most abundant proinflammatory proteins that is chronically up-regulated in AD and is found associated with senile plaques. This recognized bio-marker for brain distress may, thus, play roles in amyloid aggregation which remain to ...
Alergia a Perceves no Contexto da Síndrome Ácaros-Crustáceos-Moluscos-Baratas
Marinho, S; Gaspar, A; Morais-Almeida, M; Postigo, I; Guisantes, J; Martínez, J; Rosado-Pinto, JIntrodução: A tropomiosina dos invertebrados é o pan-alergénio que une crustáceos, moluscos, aracnídeos, insectos e parasitas, encontrando-se significativa homologia de sequência entre as proteínas dos vários grupos. Os perceves são um tipo de crustáceo particularmente apreciado e consumido no nosso país; no entanto, a alergia a este crustáceo é uma situação bastante rara da qual só existe um trabalho publicado...