2 documents found, page 1 of 1
Phenotypic Analysis of Urothelial Exfoliated Cells in Bladder Cancer via Microf...
Carvalho, S; Abreu, CM; Ferreira, D; Lima, L; Ferreira, JA; Santos, LL; Ribeiro, R; Grenha, V; Martínez-Fernández, M; Duenas, M; Suárez-Cabrera, CBladder cancer is the most common malignancy of the urinary tract, having one of the highest recurrence rates and progression from non-muscle to muscle invasive bladder cancer that commonly leads to metastasis. Cystoscopy and urine cytology are the standard procedures for its detection but have limited clinical sensitivity and specificity. Herein, a microfluidic device, the UriChip, was developed for the enrich...
Gene Expression Analyses in Non Muscle Invasive Bladder Cancer Reveals a Role f...
Dueñas, M; Pérez-Figueroa, A; Oliveira, C; Suárez-Cabrera, C; Sousa, A; Oliveira, P; Villacampa, F; Paramio, JM; Martínez-Fernández, MNon-muscle invasive bladder cancer (NMIBC) represents a crucial problem for the national health care systems due to its high rates of recurrence and the consequent need of frequent follow-ups. Here, gene expression analyses in patients diagnosed as NMIBC were performed to determine those molecular pathways involved in tumor initiation, finding that both MYC and E2F are up regulated and helps to tumor initiation...