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Phenotypic analysis of urothelial exfoliated cells in bladder cancer via microf...

Carvalho, Sandra; Abreu, Catarina M.; Ferreira, Dylan; Lima, Luís; Santos, Lúcio L.; Ribeiro, Ricardo; Grenha, Vânia; Martínez-Fernández, Mónica

Bladder cancer is the most common malignancy of the urinary tract, having one of the highest recurrence rates and progression from non-muscle to muscle invasive bladder cancer that commonly leads to metastasis. Cystoscopy and urine cytology are the standard procedures for its detection but have limited clinical sensitivity and specificity. Herein, a microfluidic device, the UriChip, was developed for the enrich...


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