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Chitosan/alginate nanogels containing multicore magnetic nanoparticles for deli...

Veloso, Sérgio Rafael Silva; Marta, Eva S.; Rodrigues, Pedro V.; Moura, Cacilda; Amorim, Carlos O.; Amaral, Vítor S.; Correa-Duarte, Miguel A.

In this study, multicore-like iron oxide (Fe3O4) and manganese ferrite (MnFe2O4) nanoparticles were synthesized and combined with nanogels based on chitosan and alginate to obtain a multimodal drug delivery system. The nanoparticles exhibited crystalline structures and displayed sizes of 20 ± 3 nm (Fe3O4) and 11 ± 2 nm (MnFe2O4). The Fe3O4 nanoparticles showed a higher saturation magnetization and heating effic...


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