7 documents found, page 1 of 1
Human immunodeficiency virus infection may be a contributing factor to monkeypo...
Alpalhão, Miguel; Sousa, Diogo; Frade, Joana Vieitez; Patrocínio, João; Garrido, Pedro Miguel; Correia, Catarina; Brazão, Cláudia; Mancha, DoraTo the Editor: An outbreak of monkeypox has emerged, and more than 13,000 cases have already been confirmed worldwide. In our department, we have 42 confirmed cases so far. All of them are cisgender males presenting with lesions in the genital, perianal, or perioral areas (Fig 1). Interestingly, we observe a disproportionate number of individuals living with the human immunodeficiency virus (HIV). Below, we pre...
Zoon Balanitis and Lichen Sclerosus: An Uncommon Association
Garrido, Pedro Miguel; Aguado-Lobo, Marta; Soares de Almeida, Luís; Borges da Costa, JoãoZoon balanitis and lichen sclerosus are both chronic inflammatory disorders of the genital mucosa that usually affect middle-aged or elderly uncircumcised men.Although the precise etiology of Zoon balanitis is still unclear, a pathogenic role of irritant and mechanical factors has been suggested. Therefore, foreskin sclerosis and phimosis caused by male genital lichen sclerosus may trigger the development of Zo...
Acute leukemia as the initial presentation of blastic plasmacytoid dendritic ce...
Garrido, Pedro Miguel; Monteiro, Pedro de Vasconcelos; Borges-Costa, João; Soares-de-Almeida, Luís; Filipe, PauloA 90-year-old man presented with a 1-month history of fatigue and rapidly progressive, widespread skin lesions. Physical examination exhibited numerous erythematous to violaceous tumors and bruise-like patches scattered through his trunk and limbs (Fig. 1a,b). Enlarged bilateral axillary lymph nodes were noted.
Photodynamic therapy in dermatology : beyond current indications
Queirós, Catarina; Garrido, Pedro Miguel; Maia Silva, João; Filipe, PauloPhotodynamic therapy (PDT) has long been used in dermatology as a therapeutic strategy for several malignant and premalignant conditions. Currently, it is approved in Europe for the treatment of actinic keratosis, squamous cell carcinoma in situ, and some forms of basal cell carcinoma, with favorable clearance rates associated with satisfying aesthetic results. Nonetheless, in the past few years, PDT has also d...
Kaposi Sarcoma in Solid Organ Transplant Recipients: A challenging Case
Macedo, Daniela; Garrido, Pedro Miguel; Fernandes, Isabel; Santana, Alice; Guerra, José; Borges-Costa, JoãoKaposi sarcoma is a low-grade vascular tumor, associated with human herpesvirus-8 infection. Solid organ transplant recipients have a much higher risk of this malignancy, with estimated incidence rates increased 84 to 500 times. The risk is even higher in some ethnic groups, already with a higher incidence of this disease. We report a case of a 37-year-old African male, a kidney transplant recipient, with ...
Atypical Clinical Manifestations of Genital Herpes Simplex Virus Infection and ...
Garrido, Pedro Miguel; Borges-Costa, JoãoGenital herpes is a sexually transmitted infection with high global prevalence. Atypical clinical presentations of herpetic infection are rare but are becoming increasingly frequent due to the growing number of immunosuppressed patients. Therapy is challenging, with a longer treatment duration being frequently needed and an important resistance rate to the common anti-viral agents. Foscarnet and cidofovir are e...
Lyme disease: Epidemiology and Cutaneous Clinical Presentations
Garrido, Pedro Miguel; Borges-Costa, JoãoLyme disease is the tick-borne disease with highest incidence in Europe and North America. Climate change seems to be modifying its geographic distribution, with spreading of endemic areas. Simultaneously, an increasingly number of cases is being diagnosed as the knowledge of its clinical presentations is growing.Most individuals come to the Dermatology visit after a tick bite or with lesions diagnosed as eryth...