10 documents found, page 1 of 1
VEGF121 como Mediador de Efeitos Cardioprotetores Pós-Hipóxia via CaSR e via da...
Zhang,Yan; Yin,Wei-hua; Yang,Fan; An,Yun-qiang; Zhou,Wei; Yu,Hui; Xie,Hong; Zhang,Yan-ling; Zhu,Yue; Shen,Xiang-chun; Tian,RuiqingResumo Fundamento: A doença cardiovascular é a principal causa de morte em todo o mundo. A apoptose mediada por hipóxia em cardiomiócitos é uma das principais causas de distúrbios cardiovasculares. O tratamento com a proteína do fator de crescimento endotelial vascular (VEGF, do inglês vascular endothelial growth factor) foi testado, mas as dificuldades operacionais limitaram seu uso. Entretanto, com os avanços...
MicroRNA-302b mitigates renal fibrosis via inhibiting TGF-β/Smad pathway activa...
Sun,Mengkui; Zhou,Wei; Yao,Fei; Song,Jianming; Xu,Yanan; Deng,Zhimei; Diao,Hongwang; Li,ShoulinRenal fibrosis is one of the most significant pathological changes after ureteral obstruction. Transforming growth factor-β (TGF-β) signaling pathway plays essential roles in kidney fibrosis regulation. The aims of the present study were to investigate effects of microRNA-302b (miR-302b) on renal fibrosis, and interaction between miR-302b and TGF-β signaling pathway in murine unilateral ureteral obstruction (UU...
miR-22 and cerebral microbleeds in brainstem and deep area are associated with ...
Hu,Jia; Zhou,Wei; Zhou,Zhiming; Yang,Qian; Xu,Junfeng; Dong,WanliIn this study, we aimed to explore the relationship among miR-22, deep cerebral microbleeds (CMBs), and post-stroke depression (PSD) 1 month after ischemic stroke. We consecutively recruited 257 patients with first-ever and recurrent acute cerebral infarction and performed PSD diagnosis in accordance with the Diagnostic and Statistical Manual IV criteria for depression. Clinical information, assessments of stro...
Clinical characteristics and therapeutic procedure for a critical case of novel...
Zhu,Juanjuan; Zhou,Wei; Zhou,Mingyu; Liu,Yang; Yang,Jing; Li,Haiyang; Zhao,XuekeAbstract The novel coronavirus pneumonia (NCP) outbreak occurred in Wuhan, China at the end of 2019. Here, we report the clinical characteristics and therapeutic procedure for a case of severe NCP. The patient was started on glucocorticoids and non-invasive ventilator treatment. After treatment, the patient’s symptoms improved, and the status was confirmed as NCP negative. Our results may provide clues for the ...
ACT Values after Neutralization Lower than Pre-heparinization ACT Leads to Lowe...
Wang,Weitie; Wang,Yongwang; Wang,Jinshan; Xu,Rihao; Chai,Junwu; Zhou,Wei; Chen,Honglei; Xue,Fenlong; Kong,Xiangrong; Kai,WangAbstract Objective: To evaluate if lower activated coagulation time (ACT) value after neutralization than preoperative ACT value was effective in reducing bleeding, operative times, and post-operative transfusions in patients underwent coronary artery bypass grafting (CABG). Methods: Retrospective selection of 398 patients from January 2014 to May 2017. Patients were divided into 2 groups according to final ACT...
Outcomes Following Coronary Artery Bypass Graft Surgery in Patients with Mild P...
Wang,Weitie; Wang,Yuefeng; Xu,Rihao; Chai,Junwu; Zhou,Wei; Chen,Honglei; Wang,Kai; Kong,XiangrongAbstract Introduction: Preoperative renal insufficiency is an independent predictor of mortality after coronary artery bypass graft (CABG) surgery. However, there are few reports aimed to evaluate the impact of mild preoperative renal insufficiency on long-term follow-up outcomes after isolated CABG surgery. This study investigates the effect of mild preoperative renal insufficiency on long-term follow-up outco...
Phenol degradation and genotypic analysis of dioxygenase genes in bacteria isol...
Tian,Mengyang; Du,Dongyun; Zhou,Wei; Zeng,Xiaobo; Cheng,GuojunAbstract The aerobic degradation of aromatic compounds by bacteria is performed by dioxygenases. To show some characteristic patterns of the dioxygenase genotype and its degradation specificities, twenty-nine gram-negative bacterial cultures were obtained from sediment contaminated with phenolic compounds in Wuhan, China. The isolates were phylogenetically diverse and belonged to 10 genera. All 29 gram-negative...
Late nitrogen application enhances spikelet number in indica hybrid rice (Oryza...
Zhou,Wei; Lv,Tengfei; Chen,Yong; Hu,Jianfeng; Zhang,Qiang; Ren,WanjunABSTRACT To increase rice yield potential, field experiments were conducted in farmers’ paddies in 2011 and 2012 to evaluate the effects of different nitrogen applications on the yield and panicle components of three typical indica hybrid rice varieties in Sichuan Province. The number of grains per panicle resulting from late nitrogen application (LA) was 12 % greater than that obtained from traditional nitroge...
A meta-analysis of efficacy and safety of doripenem for treating bacterial infec...
Qu,Xiao-Yu; Hu,Ting-Ting; Zhou,WeiObjective: The aim of this article is to compare the efficacy and safety of doripenem for bacterial infections. Methods: We included six randomized clinical trials identified from PubMed and Embase up to July 31, 2014. The included trials compared efficacy and safety of doripenem for complicated intra-abdominal infections, complicated urinary tract infection, nosocomial pneumonia, and acute biliary tract infection...
Enhancement of chitosanase production by cell immobilization of Gongronella sp. JG
Zhang,Pingping; Zhou,Wei; Wang,Peng; Wang,Li; Tang,MingliChitosanase production of Gongronella sp. JG cells immobilized in calcium alginate gel and polyurethane foam was compared with that of the free cells, there was a 60% increase in the enzyme yield (2429 U/L) compared to the highest yield obtained from free cells (1513 U/L). The optimal immobilization parameters (concentrations of sodium alginate, calcium chloride, bead inoculums, bead diameter, etc) for the enha...