13 documents found, page 1 of 2
Unlocking Nature’s Anti-Aging Secrets: The Potential of Natural Mineral Waters ...
Gama, Ana Rita; Gomes, Carolina P.; Caetano, Cátia; Oliveira, Ana Sofia; Rolo, Joana; Barros, Lillian; Plasencia, Paula; Garcia, JulianaSkin aging is influenced by intrinsic and extrinsic factors, leading to structural changes in the skin. Current anti-aging cosmetic trends emphasize innovative natural ingredients, including plant extracts, thermal waters, and botanical hydrolats. This work aims to develop six natural anti-aging cosmetics (two serums, two day creams, and two night creams) with innovative and non-irritating profiles. The rationa...
Vaginal Sheets with Thymbra capitata Essential Oil for the Treatment of Bacteri...
Tomás, Mariana; Sousa, Lúcia G. V.; Oliveira, Ana Sofia; Gomes, Carolina P.; Palmeira-de-Oliveira, Ana; Cavaleiro, Carlos; Salgueiro, Lígia; Cerca, NunoWe aimed to incorporate Thymbra capitata essential oil (TCEO), a potent antimicrobial natural product against bacterial vaginosis (BV)-related bacteria, in a suitable drug delivery system. We used vaginal sheets as dosage form to promote immediate relief of the typical abundant vaginal discharge with unpleasant odour. Excipients were selected to promote the healthy vaginal environment reestablishment and bioadh...
Study of Ecological Relationship of Yeast Species with Candida albicans in the ...
Caetano, Cátia Filipa; Gaspar, Carlos; Oliveira, Ana Sofia; Oliveira, Rita Palmeira de; Rodrigues, Lisa; Gonçalves, Teresa; Martinez-de-Oliveira, JoséThe role of the fungal community, the mycobiota, in the health of the vagina is currently an important area of research. The emergence of new sequencing technologies and advances in bioinformatics made possible the discovery of novel fungi inhabiting this niche. Candida spp. constitutes the most important group of opportunistic pathogenic fungi, being the most prevalent fungal species in vulvovaginal infections...
Vaginal sheets with Thymbra capitata essential oil for the treatment of bacteri...
Tomás, Mariana; Sousa, Lúcia Filipa Guimarães Vieira; Oliveira, Ana Sofia; Gomes, Carolina P.; Palmeira-de-Oliveira, Ana; Cavaleiro, CarlosWe aimed to incorporate Thymbra capitata essential oil (TCEO), a potent antimicrobial natural product against bacterial vaginosis (BV)-related bacteria, in a suitable drug delivery system. We used vaginal sheets as dosage form to promote immediate relief of the typical abundant vaginal discharge with unpleasant odour. Excipients were selected to promote the healthy vaginal environment reestablishment and bioadh...
Development of a new multiplex PCR to detect prevalent species of house dust mi...
Oliveira, Ana Sofia; Gaspar, Carlos; Rolo, Joana; Pereira, Cristiana Costa; Palmeira-de-Oliveira, Rita; Teixeira, João Paulo; Martinez-de-Oliveira, JoséDermatophagoides pteronyssinus and Dermatophagoides farinae are the most common House Dust Mite (HDM) species in home environments worldwide and responsible for HDM allergy. Since the prevalence of HDM-related clinical conditions is linked to exposure to the mite itself, the detection of HDM in the human households gains importance. We aimed to develop a fast and accessible multiplex PCR to detect and distingui...
Chemical characterization and bioactive potential of Thymus × citriodorus (Pers...
Oliveira, Ana S.; Rolo, Joana; Gaspar, Carlos; Cavaleiro, Carlos; Salgueiro, Lígia; Palmeira-de-Oliveira, Rita; Ferraz, Celso; Coelho, SusanaEthnopharmacological relevance: Thymus × citriodorus (Pers.) Schreb. is an interspecific hybrid between Thymus pulegioides and Thymus vulgaris, known for its pharmacological activities as diaphoretic, deodorant, antiseptic and disinfectant, the last mostly related with its antimicrobial activity. The folk use of other extracts, as hydrolates, have also been disseminated, as regulators of oily skin with anti-acn...
Thymus mastichina (L.) L. and Cistus ladanifer L. for skin application: chemica...
Oliveira, Ana S.; Rolo, Joana; Gaspar, Carlos; Ramos, Leonor; Cavaleiro, Carlos; Salgueiro, Lígia; Palmeira-de-Oliveira, Rita; Teixeira, João PauloEthnopharmacological relevance: Thymus mastichina (L.) L. (TM) and Cistus ladanifer L. (CL) are two Portuguese autochthonous species with traditional skin application in folk medicine. TM is majorly known for its antiseptic and wound healing properties, as an external anti-inflammatory agent and for its application in folk cosmetics and hygiene products. Its use in acne vulgaris has also been reported. CL is tr...
Dequalinium Chloride Effectively Disrupts Bacterial Vaginosis (BV) Gardnerella ...
Gaspar, Carlos; Rolo, Joana; Cerca, Nuno; Palmeira-de-Oliveira, Rita; Martinez-de-Oliveira, José; Palmeira-de-Oliveira, AnaBacterial vaginosis (BV) is the most frequent vaginal infection worldwide. It is caused by the overgrowth of anaerobic vaginal pathogens such as Gardnerella spp. BV has been associated with the occurrence of dense multispecies biofilms on the vaginal mucosa. Treatment of biofilm-associated infections such as BV is challenging. In this study, we have tested the role of a quaternary ammonium compound, dequalinium...
Aptamer-Functionalized Gold Nanoparticles for Drug Delivery to Gynecological Ca...
Lopes-Nunes, Jessica; Agonia, Ana S.; Rosado, Tiago; Gallardo, Eugenia; Palmeira-de-Oliveira, Rita; Palmeira-de-Oliveira, AnaCervical cancer is one of the most common cancers and is one of the major cause of deaths in women, especially in underdeveloped countries. The patients are usually treated with surgery, radiotherapy, and chemotherapy. However, these treatments can cause several side effects and may lead to infertility. Another concerning gynecologic cancer is endometrial cancer, in which a high number of patients present a poo...
Dequalinium chloride effectively disrupts bacterial vaginosis (BV) Gardnerella ...
Gaspar, Carlos; Rolo, Joana; Cerca, Nuno; Palmeira-de-Oliveira, Rita; Martinez-de-Oliveira, José; Palmeira-de-Oliveira, AnaBacterial vaginosis (BV) is the most frequent vaginal infection worldwide. It is caused by the overgrowth of anaerobic vaginal pathogens such as Gardnerella spp. BV has been associated with the occurrence of dense multispecies biofilms on the vaginal mucosa. Treatment of biofilm-associated infections such as BV is challenging. In this study, we have tested the role of a quaternary ammonium compound, dequalinium...