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Sarcoidosis and Multiple Myeloma: A Case Report and Literature Review

Serra, J; Martinho, A; Duarte, F; Aldomiro, F

The existence of a sarcoidosis-lymphoma syndrome has been previously proposed since the relation between sarcoidosis and an increased risk of lymphoproliferative disorders is well established. Multiple myeloma is a malignant multifocal proliferation of clonal plasma cells within the bone marrow, and its association with sarcoidosis has been rarely described. We present a concurrent diagnosis of sarcoidosis and ...


INVAGINAÇÃO INTESTINAL SECUNDÁRIA A LINFOMA DE BURKITT EM CÃO JOVEM

Alexandre, N; Martinho, A; Moreira, J; Pestana, S; Caldeira, J; Branco, S

Foi presente à consulta uma cadela de 11 meses de idade de raça indeterminada por motivo de abdómen agudo. Na história pregressa verificou-se que existia a suspeita de ingestão de corpo estranho (CE) no dia anterior à consulta, vómito incoercível com 24 horas de duração, dor abdominal e anorexia parcial. Ao exame clínico, registaram-se diversas alterações entre as quais a presença de mucosa oral congestionada, ...


Drug reaction with eosinophilia and systemic symptoms caused by spironolactone:...

Fernandes, RA; Regateiro, FS; Faria, E; Martinho, A; Gonçalo, Margarida; Todo‐Bom, A


Lifelong training improves anti-inflammatory environment and maintains the numb...

Minuzzi, LG; Rama, L; Bishop, NC; Rosado, F; Martinho, A; Paiva, A; Teixeira, AM

PURPOSE: The purpose of this study was to quantify and characterize peripheral blood regulatory T cells (Tregs), as well as the IL-10 plasma concentration, in Masters athletes at rest and after an acute exhaustive exercise test. METHODS: Eighteen Masters athletes (self-reported training: 24.6 ± 1.83 years; 10.27 ± 0.24 months and 5.45 ± 0.42 h/week per each month trained) and an age-matched control group of ten...




Candida species contamination of preservation fluid-outcome of renal transplant...

Rodrigues, B; Natário, A; Vizinho, R; Jorge C, C; Weigert, A; Martinho, A; Toscano, C; Marques, T; Machado, D

BACKGROUND: Fungal infections are a rare but important cause of morbidity and mortality in kidney transplantation. Fungal contamination of the kidney preservation fluid may, sometimes, be the cause of these infections. However, the clinical consequences of fungal contamination of this fluid are not completely understood and literature on this topic is controversial. The purpose of this study was to determine th...


Tumores oncocíticos da supra-renal

Capela, A; Martinho, A; Duarte, F; Garcia, H; Pires, F; Manso, RT; Aparício, S; Costa, A

RESUMO Os tumores oncocíticos da supra-renal são neoplasias pouco frequentes. Atualmente existem 147 casos publicados. Os autores descrevem o caso de um homem de 34 anos admitido no hospital por lombalgias e febre. À observação identificava-se massa no quadrante superior esquerdo do abdomen. Os doseamentos das hormonas da supra-renal foram normais e a angiotomografia abdominal mostrou lesão retroperitoneal esqu...


Paralisia por hipocaliémia: manifestação inaugural da síndrome de Sjögren primário

Martinho, A; Capela, A; Duarte, F

O Síndrome de Sjögren é uma doença auto-imune sistémica caracterizada por inflamação crónica das glândulas exócrinas. As manifestações extraglandulares têm uma incidência até 25%. O envolvimento renal ocorre em 18,4-67% dos casos, e nestes a nefrite tubulointersticial é a lesão mais frequente. Apresenta-se o caso clínico de uma mulher de 37 anos, internada por fraqueza muscular generalizada de grau 2 com uma se...


Tolerogenic versus Inflammatory Activity of Peripheral Blood Monocytes and Dend...

Carvalheiro, T; Rodrigues, A; Lopes, A; Velada, I; Ribeiro, A; Martinho, A; Inês, L; Pereira da Silva, JA; Pais, ML; Paiva, A

Abnormalities in monocytes and in peripheral blood dendritic cells (DC) subsets have been reported in systemic lupus erythematosus (SLE). We aim to clarify the tolerogenic or inflammatory role of these cells based on ICOSL or IFN-α and chemokine mRNA expression, respectively, after cell purification. The study included 18 SLE patients with active disease (ASLE), 25 with inactive disease (ISLE), and 30 healthy c...


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