373 documents found, page 1 of 38
Conductive biological materials for in vitro models: properties and sustainabil...
Serafin, Aleksandra; Casanova, César David Rodrigues; Chandel, Arvind K. Singh; Reis, R. L.; Oliveira, J. M.; Collins, Maurice N.The integration of conductive biological materials into in vitro models represents a transformative approach to advancing biomedical research while addressing critical sustainability challenges. Traditional materials used in tissue engineering and disease modeling are often environmentally detrimental, derived from non-renewable resources, and limited in their ability to replicate the dynamic properties of nati...
Determination of free and glycosidically-bound fractions responsible of grape m...
Vilanova, Mar; Oliveira, J. M.The analysis of volatile composition in grape musts is an important tool to characterize grape cultivars and to determine the influence of biotic and abiotic stresses in this composition. One of the most common methods used for sample preparation to identify and quantify the volatile compounds is solid-phase extraction (SPE). The purpose of this work is to describe SPE methodology applied to grape must to ident...
Guia para o uso do Sistema Internacional de Unidades (SI)
Peixoto, J.; Oliveira, J. M.Apesar das evidentes vantagens de se utilizar um sistema decimal de unidades, coerente e universal, são muito variadas as resistências à mudança, vindas dos mais diversos setores da indústria, comércio, ensino e comunidade científica. Assim, este guia pretende compilar, num formato simples e prático, informação relevante que possa ser usada na correta aplicação do Sistema Internacional de Unidades (SI). São apr...
Sickle cell disease: current drug treatments and functional foods with therapeu...
Gonçalves, Elisângela; Smaoui, Slim; Brito, Miguel; Oliveira, J. M.; Arez, Ana Paula; Tavares, LolenySickle cell anemia (SCA), the most common form of sickle cell disease (SCD), is a genetic blood disorder. Red blood cells break down prematurely, causing anemia and often blocking blood vessels, leading to chronic pain, organ damage, and increased infection risk. SCD arises from a single-nucleotide mutation in the β-globin gene, substituting glutamic acid with valine in the β-globin chain. This review examines ...
As dissidências das normas de género: História de vida e singularidades de Ariel
Pereira, V.; Oliveira, J. M.; Joaquim, T.Neste artigo pretende-se explorar as experiências narradas na história de vida de uma pessoa intersexo que transitou socialmente de género, aprofundando a temática da dissidência nas suas dimensões mais significativas. Em termos metodológicos realizou‑se um estudo qualitativo, no qual se recolheu a sua história de vida através de entrevistas não estruturadas, tendo a análise temática do corpus sido realizada fe...
Anodic oxidation of 3D printed Ti6Al4V scaffold surfaces: In vitro studies
Sousa, Talita Kathleen Correia de; Maia, Fátima Raquel; Pina, Sandra Cristina Almeida; Reis, R. L.; Oliveira, J. M.; Carobolante, João Pedro AquilesThis study focuses on the surface modification of Ti6Al4V scaffolds produced through additive manufacturing using the Powder-Bed Fusion Electron-Beam Melting (PBF-EB) technique. From our perspective, this technique has the potential to enhance implant osseointegration, involving the growth of a layer of titanium dioxide nanotubes (TiO2) on surfaces through anodic oxidation. Scaffolds with anodized surfaces were...
Sustainable highly stretchable and tough gelatin-alkali lignin hydrogels for sc...
Decante, Guy Bandouin Henri; Cengiz, I. F.; Costa, João B.; Collins, Maurice N.; Reis, R. L.; Silva-Correia, Joana; Oliveira, J. M.Hydrogels and bioinks obtained from gelatin (Gel) generally present poor mechanical properties and require a series of time-consuming and stepwise chemical processes to exhibit improved elasticity and resistance to fatigue. Alkali lignin (AL) is an underutilized by-product of the paper and pulp industry. It is a widely available and inexpensive biomaterial that presents enormous potential for high-value applica...
Hydrogels for tissue engineering and regenerative medicine: from fundamentals t...
Oliveira, J. M.; Silva-Correia, Joana; Reis, R. L.Hydrogels are among the most important and used biomaterials for tissue engineering and regenerative medicine (TERM) strategies. This is mostly due to their similarities to the native extracellular matrix of tissues. Their hydration capacity and suitable porosity are crucial for the process of exchanging of nutrients/metabolites and gases that is required for maintaining functions and growth of normal cells. By...
18Ni300 maraging steel lattice structures fabricated via laser powder bed fusio...
Oliveira, D. F.; Vieira, J. S.; Duarte, Isabel; Vincze, G.; Oliveira, J. M.; Miranda, G.Maraging steels have attracted the attention of the injection molding industry, mainly due to their mechanical properties. However, the use of these steels for complex inserts is still a challenge, given the limitations of conventional subtractive technologies. In this context, additive manufacturing technologies, especially Laser powder bed fusion (LPBF), arise as a solution for the manufacture of maraging ste...
Repairing annulus fibrosus fissures using methacrylated gellan gum combined wit...
Croft, Andreas F.; Ćorluka, Slavko; Fuhrer, Janine; Wöltje, Michael; Silva-Correia, Joana; Oliveira, J. M.; Erbach, Georg F.; Reis, R. L.Intervertebral disc (IVD) herniation often causes severe pain and is frequently associated with the degeneration of the IVD. As the IVD degenerates, more fissures with increasing size appear within the outer region of the IVD, the annulus fibrosus (AF), favoring the initiation and progression of IVD herniation. For this reason, we propose an AF repair approach based on methacrylated gellan gum (GG-MA) and silk ...