16 documents found, page 1 of 2

Case Report

Funding Information: The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. The present publication was funded by Funda\u00E7\u00E3o Ci\u00EAncia e Tecnologia, IP national support through UID/04923 - Comprehensive Health Research Centre. Acknowledgments Publisher Copyright: Copyright © 2025 Andrade, Cordeiro, Pinto, Neves, Martins, Villartay a...

Programmed death-ligand 1 (PD-L1) expression in cervical intraepithelial neopla...

Funding: Open access funding provided by FCT|FCCN (b-on).; Programmed death-ligand 1 (PD-L1) is overexpressed in cervical carcinoma, hindering tumor destruction. The aim of this study was to assess PD-L1 expression by immunohistochemistry in cervical squamous cell carcinoma (SCC) and squamous intraepithelial lesions (SILs) from human immunodeficiency virus–positive (HIV+) and human immunodeficiency virus-negati...

Self-care in the person with chronic disease

Funding Information: This project was supported by the Comprehensive Health Research Centre (CHRC) with registered number NCT06235593 . Funding Information: This work is funded by nationalfunds through the Foundation for Science and Technology, under the project UIDP/04923/2020. Publisher Copyright: © 2024; Most aging populations report chronic illnesses, which are usually permanent or recurrent, significantly ...

Recurrent infections and short stature – Listening may be the key. A Bloom synd...

Introduction: Bloom syndrome is a rare autosomal recessive disorder characterized by chromosomal instability caused by mutations in the BLM gene that increase the risk of developing neoplasia, particularly at an early age. Bloom syndrome is typically characterized by short stature, photosensitivity, telangiectatic erythema, learning difficulties, immunodeficiency, and malignancy. Case report: We report a case o...

Histamina e seus recetores

Histamine is one of the main mediators involved in immune homeostasis, presenting a myriad of functions. Four histamine receptors (HR) are currently known, being HR1 the best characterized and recognized for its association with allergic diseases pathophysiology. HR2 is known for its involvement in gastric pathology, HR3 for its neuromodulatory role and, more recently, HR4, considered to be involved also in all...

Natural Killer Cell Receptors and Endometriosis

Funding: This work in the context of the “Women’s Health and Maternal & Fetal Research Group” was partially co-financed by Hospital da Luz Lisboa under the initiative “Luz Investigação”.; Endometriosis is a chronic inflammatory disorder, characterized by the presence of endometrial cells outside the uterine cavity. An increasing number of studies correlate the immune system with endometriosis, particularly NK r...

Hemophagocytic lymphohistiocytosis in an adolescent with NLRP12-related autoinf...

Kinetics of Torque Teno Virus Viral Load Is Associated with Infection and De No...

Funding Information: The present publication was funded by Fundação Ciência e Tecnologia, IP national support through CHRC (UIDP/04923/2020). Publisher Copyright: © 2023 by the authors.; Torque teno virus (TTV) was recently identified as a potential biomarker for the degree of immunosuppression, and potentially as a predictor of rejection and infection in solid organ transplant patients. We evaluated TTV viral ...

Association of B Cells with Idiopathic Recurrent Pregnancy Loss

Recurrent pregnancy loss (RPL) affects 1-2% of women and is defined as having experienced two or more failed pregnancies. In almost 50% of cases, the causes are idiopathic (IRPL), but increasing evidence has suggested an immunological cause. B cells are known to provide crucial support for a successful pregnancy outcome. However, their involvement in the mechanisms underlying IRPL is still unclear. This systema...

Case Report

Funding Information: The present publication was funded by Fundação Ciência e Tecnologia, IP national support through CHRC (UIDP/04923/2020). Funding Information: We thank our colleagues at “Centro de Genética Preditiva e Preventiva, Instituto de Biologia Molecular e Celular, Instituto de Investigacão e Inovacaão em Saúde, Porto” and Laboratory of Immunology, NOVA Medical School, Lisboa. The present publication...