Bio-based and natural building materials can support the building sector to reduce its environmental impact. In this study, experimental research was developed to evaluate the performance of giant reed when used as a building thermal insulation. Reed was chosen due to its high availability and close relationship to Portuguese vernacular architecture. The role of the reed’s origin in this context, its physical c...
Silica aerogels are highly porous materials with exceptional thermal insulation performance. They become even more attractive if combined thermal and acoustic insulation is achieved. Silica aerogel composites reinforced with fibres are an ingenious way to surpass the fragility stemmed from the aerogel’s intrinsic porosity, and textile fibres are good sound absorption materials. Reclaimed fibres are a relatively...
A crescente disseminação de produtos farmacêuticos no ambiente resultante das descargas de efluentes domésticos e hospitalares (ou da indústria farmacêutica) tem agravado a poluição dos ecossistemas aquáticos constituindo um complexo e desafiador problema de saúde pública. Os antibióticos são um dos grupos de fármacos mais usados no tratamento humano e veterinário, verificando-se que o controlo da presença dest...
Infection is a major issue in chronic wound care. Different dressings have been developed to prevent microbial propagation, but an effective, all-in-one (cytocompatible, antimicrobial and promoter of healing) solution is still to be uncovered. In this research, polyvinyl alcohol (PVA) nanofibrous mats reinforced with cellulose nanocrystal (CNC), at 10 and 20% v/v ratios, were produced by electrospinning, crossl...
In this research, we propose to engineer a nanostructured mat that can simultaneously kill bacteria and promote an environment conducive to healing for prospective wound care. Polyvinyl alcohol (PVA) and cellulose acetate (CA) were combined at different polymer ratios (100/0, 90/10, 80/20% v/v), electrospun and crosslinked with glutaraldehyde vapor. Crosslinked fibers increased in diameter (from 194 to 278 nm),...
In the past few years, the outstanding properties of the best-known derivative of graphene, the graphene oxide (GO), have led to a wide increase of its spectra of application. GO-based composites have been reported as chemically and mechanically stable, presenting good biocompatibility and great antimicrobial potential. Also, GO's two-dimensional planar structure coupled with its large availability of oxygen-re...
[Excerpt] Essential oils (EOs), which are complex biomolecules composed of volatile compounds, have emerged as a new strategy to deal with bacterial infections and as a valid alternative to synthetic drugs in the treatment of chronic wounds (CW) by promoting the regeneration of damaged tissues.
Nisin Z, an amphipathic peptide, with a significant antibacterial activity against Gram-positive bacteria and low toxicity in humans, has been studied for food preservation applications. Thus far, very little research has been done to explore its potential in biomedicine. Here, we report the modification of sodium alginate (SA) and gelatin (GN) blended microfibers, produced via the wet-spinning technique, with ...
Wet-spinning is a non-solvent induced phase inversion technique that allows the production of continuous polymeric microfibers, with a uniform morphology, based on the principle of precipitation. It allows the production of 3D fibrous constructs with an intricated architecture that facilitates cell infiltration, something that is very limited in electrospun nanofibrous mats, thus increasing its interest in biom...
[Excerpt] The aim of this study was to produce SA/GN microfibers via wet-spinning technique, and subsequently functionalize these fibers with Nisin Z, in order to map Nisin Z’s controlled release kinetics and antimicrobial action against S. aureus