Children with COVID-19 typically experience milder symptoms and lower hospitalization rates, though severe cases do occur. Understanding age-related immune responses is crucial for future preparedness. We characterized immune response dynamics to SARS-CoV-2 in 145 samples from 119 pediatric patients (<18 years) with confirmed infection, assessed at four distinct time points: <14 days, 14 days-3 months, 3-6 mont...
In recent years, there has been an increase in demographic ageing in Portugal and the prevalence of depression in elderlies living in nursing homes. Frailty and independence loss may contribute to the increase in depression among the elderly. Exercise has been suggested as an effective intervention, with no negative secondary effects, to avoid the increased rate of age-related loss of functionality and independ...
Ageing is an irreversible natural and normal life process that leads to function loss, often associated with sarcopenia and increased dependence on others. Physical exercise induces an improvement in muscle function, counteracting the effects of ageing and potentially delaying dependence. The main objective of this study was to measure the effect of a physical exercise program on physical fitness, sarcopenia, a...
One of the leading age-related changes affecting most older adults is the worsening of sleep quality. The literature suggests that the reduction of daily physical activity and increased frequency of daytime sleep periods in older adults are some of the main events contributing to the reduction in sleep quality, which may also negatively affect cognitive function. Considering this, it is expected that older peop...
Este livro apresenta-se como um manual introdutório aos Feminismos Pós-coloniais e Decoloniais e às temáticas relacionadas com os feminismos de mulheres racializadas e os feminismos do Sul global. Baseia-se na experiência acumulada na lecionação da disciplina “Mulheres, Raça e Etnicidades” do Doutoramento em Estudos Feministas da Faculdade de Letras da Universidade de Coimbra/Centro de Estudos Sociais. Estrutur...
'Concordância e Diferença' festeja a vida ativa do filósofo e professor João Maria André, acolhendo testemunhos e gestos de quem o conhece, admira e com quem ele privou ao longo de muitos anos de viva amizade. É convicção de todas as autoras e autores, reunidos em torno deste volume de agradecimento, que, ao longo destas páginas ressoa, numa abrangente tematização, a escuta, a hospitalidade e a capacidade refle...
Background: Acute pancreatitis (AP) is an inflammatory disease of the pancreas with incompletely known pathogenic mechanisms. This study aimed to explore the temporal changes in serum cytokines in patients with AP and to assess the association of these changes with disease severity. Methods: Fifty patients hospitalized with AP were enrolled, and their serum cytokine levels were analyzed at four different time p...
Endometriosis, a debilitating condition, affects one in ten women of reproductive age. Its pathophysiology remains unclear, though deficiencies in immune surveillance are thought to create an environment conducive to the evasion of ectopic endometrial cells from the immune system. Our research explores the immunological impact of endometriosis both locally and systemically, emphasizing natural killer (NK) and T...
Nos dias de hoje as empresas procuram a inovação como forma de afirmação no mercado nacional e internacional. Assim, aleando os conceitos de sustentabilidade e a inovação, a indústria têxtil investiga novas moléculas, pigmentos de origem natural, que possam vir a ser substituintes de moléculas de síntese química. Os pigmentos naturais são substâncias que se encontram na natureza e que podem ser extraídas de pla...
Brochura de sala do concerto realizado pelos Jovens Solistas da Metropolitana a 9 de Junho de 2023 no MUSEU NACIONAL DA MÚSICA em Lisboa no âmbito da Temporada 2022/2023 da Metropolitana. Este concerto foi realizado em parceria com a Escola Superior de Música de Lisboa do Instituto Politécnico de Lisboa e a Escola do Teatro Musical - Primeiro Acto. O programa do concerto foi preenchido com obras de Brahms, Doni...